NCT07750093

Brief Summary

The goal of this clinical trial is to compare the frequency of post-circumcision complications (bleeding, infection, and delayed ring separation) time for ring separation and level of parental satisfaction following local application of Polyfax versus coconut oil after Plastibell circumcision in infants in. Patient undergoing Plastibell circumcision will be divided into 2 groups, we will prescribe Polyfax to one group as a part of post circumcision care and coconut oil to the other group. Division into groups will be random using the lottery method, participant will visit the clinic at 1 week, 3 months and 6 months. A questionnaire will be filled by the doctor.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P50-P75 for not_applicable

Timeline
3mo left

Started Jul 2025

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress83%
Jul 2025Oct 2026

Study Start

First participant enrolled

July 1, 2025

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2026

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

August 1, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 6, 2026

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2026

Expected
Last Updated

August 6, 2026

Status Verified

August 1, 2026

Enrollment Period

1.1 years

First QC Date

August 1, 2026

Last Update Submit

August 1, 2026

Conditions

Circumcision, Male

Outcome Measures

Primary Outcomes (1)

  • Complications

    Post circumcision bleeding, infection, delayed ring seperation

    3 months

Secondary Outcomes (1)

  • Parental satisfaction

    3 month

Study Arms (2)

Coconut oil group

EXPERIMENTAL

coconut oil used for local application

Other: agent used for local application

Polyfax

EXPERIMENTAL

Polyfax for local application

Other: agent used for local application

Interventions

agent used for local applicationOTHER

agent used for local application post procedure

Coconut oil groupPolyfax

Eligibility Criteria

Age1 Week - 6 Months
Sexmale(Gender-based eligibility)
Gender Eligibility Detailsmales
Healthy VolunteersNo
Age GroupsChild (0-17)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Liaquat National Hospital

Karachi, Pakistan

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident

Study Record Dates

First Submitted

August 1, 2026

First Posted

August 6, 2026

Study Start

July 1, 2025

Primary Completion

July 31, 2026

Study Completion (Estimated)

October 31, 2026

Last Updated

August 6, 2026

Record last verified: 2026-08

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)