Perineal Ultrasound, Post-Void Residual, and Lower-Limb Alignment in Stress Incontinence

NCT07747727 | Recruiting DMC

• 1 other identifier: PT. BU. EC. 45
• Study Type: observational
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

Stress urinary incontinence (SUI) in postmenopausal women is traditionally considered a local pelvic floor disorder, but emerging evidence suggests that spinopelvic and lower limb alignment may also contribute to continence mechanisms. Transperineal ultrasound α/β angles and post void residual (PVR) volume are promising imaging markers that might capture this broader biomechanical phenotype. Objective To compare hip ultrasound α/β angles, PVR volume, and lower limb and spinopelvic alignment between symptomatic and asymptomatic postmenopausal women, and to explore within group correlations between PVR and musculoskeletal alignment variables.

Conditions

Stress Urinary Incontinence in Women

Keywords

Stress Urinary Incontinence; Postmenopause; Ultrasonography; Postvoid Residual Urine; Lower Extremity

Outcome Measures

Primary Outcomes (1)

• hip ultrasound parameters

  we measured hip ultrasound angles describing urethrovesical and retrovesical configurations at rest and during a Valsalva or valgus manoeuvre, expressed in degrees. Trained clinicians performed transperineal ultrasound examinations in the lithotomy or semi-recumbent position, capturing angle measurements at rest and during standardized Valsalva efforts; we then recorded the mean of repeated readings to reduce measurement error.

  At a single study visit (baseline)

Secondary Outcomes (3)

• Lower-Limb and Foot Posture Measures

  At a single study visit (baseline)

• Spinopelvic Alignment and Torsion

  At a single study visit (baseline)

• Post-Void Residual Volume

  At a single study visit (baseline)

Study Arms (2)

symptomatic stress urinary incontinence

they reported stress-related urine leakage during effort, exertion, sneezing, or coughing and had an International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) or equivalent score above a predefined threshold ≥6).

asymptomatic controls (Normal group)

they reported no involuntary urine leakage in the preceding 12 months and had an ICIQ-SF score between 0 and 2; both cases and controls

Eligibility Criteria

• Age: 50 Years - 65 Years
• Gender Eligibility Details: post menoupausal women
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

included postmenopausal women aged 50 years or older who had at least 12 months of amenorrhea or follicle-stimulating hormone values within the menopausal range and who could stand and walk independently to allow lower-limb and alignment assessments

Sponsors & Collaborators

• Benha University: lead

Study Sites (1)

out patient clinic, Faculty of Physical Therapy, Benha University

Banhā, Qalyoubia, 13518, Egypt

RECRUITING

MeSH Terms

Conditions

Urinary Incontinence, Stress

Condition Hierarchy (Ancestors)

Urinary Incontinence; Urination Disorders; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Lower Urinary Tract Symptoms; Urological Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Aliaa M Elabd, assistant professor

  Faculty of Physical Therapy, Benha University

  STUDY DIRECTOR

Central Study Contacts

Aliaa M Elabd, assistant professor

CONTACT

00201069352446; aliaelabd88@gmail.com

Omar M Elabd, PhD

CONTACT

00201098221045; aliaelabd88@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant professor

Study Record Dates

• First Submitted: July 31, 2026
• First Posted: August 5, 2026
• Study Start: February 3, 2026
• Primary Completion: August 2, 2026
• Study Completion (Estimated): August 15, 2026
• Last Updated: August 5, 2026

Record last verified: 2026-07

Locations

EG (1)