The Effect of Brain Endurance Training on Motor Skill Learning in Adolescents With Mild Mental Fatigue

NCT07746557 | Not Yet Recruiting DMC

• 1 other identifier: TJUS2025-134
• Study Type: interventional
• Target: 58
• Locations: 0 countries
• Sites: N/A

Brief Summary

Objective: To investigate the effects of brain endurance training on improving motor skill learning in adolescents with mild mental fatigue. Methods: Fifty-eight adolescents experiencing mild mental fatigue were recruited. A 6-week training program was conducted using a 2 (BET group, control group) × 2 (pre- and post-Stroop task) × 3 (0, 3, 6 weeks) mixed-design experimental design. Assessments included basketball free throws, the Visual Analog Scale (VAS-MF), the 3-minute Psychomotor Vigilance Test (PVT-B), the Borg Rating of Perceived Exertion (RPE) to assess performance before and after a 30-minute Stroop task.

Conditions

Mental Fatigue; Motor Skill Learning

Outcome Measures

Primary Outcomes (3)

• Number of Free Throws Made in Basketball

  From enrollment through Week 3 and then Week 6

• Number of Free Throws in 1 Minute

  From enrollment through Week 3 and then Week 6

• Free throws made in 1 minute

  From enrollment through Week 3 and then Week 6

Secondary Outcomes (3)

• VAS-MF

  From enrollment through Week 3 and then Week 6

• RPE

  From enrollment through Week 3 and then Week 6

• At the time of the reaction

  From enrollment through Week 3 and then Week 6

Study Arms (2)

BET

EXPERIMENTAL

During training, the BET group completed a 20-minute 2-back task \[28\]; after a 5-minute break, they performed free-throw-related physical and technical training. The training content, intensity, and workload were identical for both groups, and the presentation timing and intervals of the 2-back task stimuli were adjusted every two weeks \[18\]. During testing, both the BET group and the control group completed 20 free-throw attempts and a 1-minute free-throw test \[29\] before and after the 30-minute Stroop task, and underwent PVT-B, VAS-MF, and RPE assessments.

Behavioral: Motor Skill Learning

Control

EXPERIMENTAL

The BET group and the control group underwent the same physical and technical training related to free throws; the training content, intensity, and workload were identical for both groups. While the BET group performed cognitive tasks, the control group rested in place. The presentation timing and intervals of the 2-back task stimuli were adjusted every two weeks \[18\]. During testing, both the BET group and the control group completed 20 free-throw trials and a 1-minute free-throw test \[29\] before and after the 30-minute Stroop task, and underwent PVT-B, VAS-MF, and RPE assessments.

Behavioral: Motor Skill Learning

Interventions

Motor Skill Learning BEHAVIORAL

During training, the BET group completed a 20-minute 2-back task \[28\], followed by a 5-minute break, after which they performed free-throw-related physical and technical training. The presentation timing and intervals of the 2-back task stimuli were adjusted every two weeks \[18\]. During testing, the BET group completed 20 free-throw trials and a 1-minute free-throw test \[29\] before and after the 30-minute Stroop task, and underwent PVT-B, VAS-MF, and RPE assessments.

BET

Eligibility Criteria

• Age: 18 Years - 19 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Participants assessed as having mild mental fatigue using the Mental Fatigue VAS scale
• No prior experience in learning specific motor skills
• In good physical health, with no history of central nervous system disorders, musculoskeletal injuries, or mental health conditions

You may not qualify if:

• Individuals with moderate to severe mental fatigue or no mental fatigue
• Individuals with moderate to severe mental fatigue or no mental fatigue
• Individuals with a history of traumatic brain injury, epilepsy, chronic headaches, ADHD, anxiety, or depression - Individuals who have sustained a musculoskeletal injury within the past month and are unable to complete standardized exercise routines
• Individuals taking medications that affect central nervous system function on a long-term basis, or who have consumed caffeine, energy drinks, or alcohol within 24 hours prior to the experiment - Individuals with persistent sleep disorders
• Individuals unable to cooperate in completing cognitive endurance training and motor skill tests.Individuals with a history of traumatic brain injury, epilepsy, chronic headaches, ADHD, anxiety, or depression
• Individuals who have sustained a musculoskeletal injury within the past month and are unable to complete standardized exercise routines
• Individuals taking medications that affect central nervous system function on a long-term basis, or who have consumed caffeine, energy drinks, or alcohol within 24 hours prior to the experiment
• Individuals with persistent sleep disorders - Individuals unable to cooperate in completing cognitive endurance training and motor skill tests.

Sponsors & Collaborators

• Yunliang Zhang: lead

Related Links

• Related Info

MeSH Terms

Conditions

Mental Fatigue

Condition Hierarchy (Ancestors)

Fatigue; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavioral Symptoms; Behavior

Central Study Contacts

Yunliang ZHANG

CONTACT

+8613920900801; yunliangzhang@126.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: July 25, 2026
• First Posted: August 5, 2026
• Study Start: August 2, 2026
• Primary Completion (Estimated): September 13, 2026
• Study Completion (Estimated): September 19, 2026
• Last Updated: August 5, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will share