NCT07745972

Brief Summary

The aim of the study is to reduce postoperative pain by performing rectointercostal block in L/S cholecystectomy surgeries. Main goal is to provide well managed post-operative analgesia.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
5mo left

Started Aug 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress3%
Aug 2026Dec 2026

First Submitted

Initial submission to the registry

July 23, 2026

Completed
9 days until next milestone

Study Start

First participant enrolled

August 1, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 4, 2026

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2026

Last Updated

August 4, 2026

Status Verified

July 1, 2026

Enrollment Period

5 months

First QC Date

July 23, 2026

Last Update Submit

July 30, 2026

Conditions

Keywords

CholesistectomyRectointercostal Plane BlockPostoperative Pain

Outcome Measures

Primary Outcomes (1)

  • Postoperative opioid consumption

    Contramal consumption in the first 24 hours after surgery

    24 hours

Secondary Outcomes (3)

  • NRS Scores

    At 1,3, 6, 12, 18, 24 hours

  • Quality of recovery

    24 hours

  • Nausea and vomiting

    At 1,3, 6, 12, 18, 24 hours

Study Arms (2)

Block

EXPERIMENTAL

Recto intercostal Plane Block Group

Procedure: Rectointercostal facial plane block using bupivacaine 0.25%

Control

NO INTERVENTION

Control Group

Interventions

Under ultrasound guidance, a total of 30 mL of solution will be administered bilaterally between the rectus abdominis muscle and the intercostal muscles, at the level of the 6th and 7th costal cartilages bilaterally.

Block

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • BMI \< 35 kg/m²
  • Patients with ASA scores I and II

You may not qualify if:

  • Patients who do not want to be included in the study
  • Psychiatric and neurological disease with blurred consciousness
  • Patients with ASA \> 3
  • BMI \> 35 kg/m²
  • Abnormality in coagulation parameters
  • History of allergy to local anesthetic drugs
  • Infection at the injection site

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Istinye University Liv Topkapı Hospital

Istanbul, 34050, Turkey (Türkiye)

Location

Related Publications (1)

  • Tulgar S, Ahiskalioglu A, Aydin ME, De Cassai A. Recto-intercostal fascial plane block for upper abdominal analgesia: the ultimate solution? Korean J Anesthesiol. 2025 Oct;78(5):504-505. doi: 10.4097/kja.25355. Epub 2025 Jun 9. No abstract available.

    PMID: 40485137BACKGROUND

MeSH Terms

Conditions

AgnosiaPain, Postoperative

Condition Hierarchy (Ancestors)

Perceptual DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsPostoperative ComplicationsPathologic ProcessesPain

Central Study Contacts

Bora Bilal, Proffesor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Proffesor MD

Study Record Dates

First Submitted

July 23, 2026

First Posted

August 4, 2026

Study Start

August 1, 2026

Primary Completion (Estimated)

December 31, 2026

Study Completion (Estimated)

December 31, 2026

Last Updated

August 4, 2026

Record last verified: 2026-07

Data Sharing

IPD Sharing
Will not share

Locations