Quadro-Iliac Plane Block for Analgesia After Lumbar Microdiscectomy

NCT07695987 | Recruiting

• 1 other identifier: Quadroiliac plane block RCT
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This study will evaluate whether ultrasound-guided quadro-iliac plane block provides better postoperative pain control than local infiltration analgesia in patients undergoing single-level lumbar microdiscectomy. Adult patients scheduled for elective single-level lumbar microdiscectomy will be randomly assigned to receive either bilateral quadro-iliac plane block plus patient-controlled analgesia or local infiltration analgesia plus patient-controlled analgesia. The main outcome of the study will be total fentanyl consumption during the first 24 hours after surgery. Pain scores, need for rescue analgesia, opioid-related side effects, patient satisfaction, and recovery quality will also be evaluated.

Conditions

Pain Management

Outcome Measures

Primary Outcomes (1)

• Total Fentanyl Consumption During the First 24 Hours After Surgery

  Total postoperative fentanyl consumption administered via patient-controlled analgesia will be recorded during the first 24 hours after surgery.

  Postoperative 0-24 hours

Secondary Outcomes (5)

• Postoperative Pain Scores at Rest and During Movement

  Postoperative 0, 1, 6, 12, and 24 hours

• Number of Patients Require Rescue Analgesic

  Postoperative 0-24 hours

• Opioid-Related Adverse Effects

  Postoperative 0-24 hours

• Quality of Recovery Score

  Postoperative 24 hours

• Dermatomal Sensory Spread

  Postoperative 2 hours

Study Arms (2)

Quadro-Iliac Plane Block Group

ACTIVE COMPARATOR

Participants in this group will receive bilateral ultrasound-guided quadro-iliac plane block before emergence from general anesthesia, followed by postoperative fentanyl-based patient-controlled analgesia.

Procedure: Ultrasound-Guided Quadro-Iliac Plane Block

Local Infiltration Analgesia Group

ACTIVE COMPARATOR

Participants in this group will receive surgeon-performed local infiltration analgesia, followed by postoperative fentanyl-based patient-controlled analgesia.

Procedure: Local Infiltration Analgesia (LIA)

Interventions

Local Infiltration Analgesia (LIA) PROCEDURE

Local infiltration analgesia will be performed by the surgeon before the end of surgery. A total dose of 50 mg of 0.25% bupivacaine will be infiltrated into the subcutaneous tissue. All participants will receive postoperative fentanyl-based patient-controlled analgesia.

Local Infiltration Analgesia Group

Ultrasound-Guided Quadro-Iliac Plane Block PROCEDURE

Bilateral ultrasound-guided quadro-iliac plane block will be performed before emergence from general anesthesia in the prone position. After visualization of the quadratus lumborum muscle and iliac crest at the L3 level, 30 mL of 0.167% bupivacaine will be injected into the interfascial plane on each side. All participants will receive postoperative fentanyl-based patient-controlled analgesia.

Quadro-Iliac Plane Block Group

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 18 to 75 years
• American Society of Anesthesiologists physical status I to III
• Scheduled for elective single-level lumbar microdiscectomy, such as L4-L5 or L5-S1 disc herniation
• Planned surgery under general anesthesia
• Able to provide written informed consent

You may not qualify if:

• Allergy or hypersensitivity to local anesthetics
• Coagulopathy or active anticoagulant use
• Infection, scar tissue, or skin lesion at the injection site
• Pregnancy or breastfeeding
• Chronic pain syndrome or regular opioid use
• American Society of Anesthesiologists physical status IV or higher
• Planned surgery for two or more levels of disc herniation

Sponsors & Collaborators

• Kanuni Sultan Suleyman Training and Research Hospital: lead

Study Sites (1)

Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital

Istanbul, Istanbul, 34303, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Agnosia

Condition Hierarchy (Ancestors)

Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Engin ihsan Turan, principal investigator

CONTACT

+905382431114; drenginihsan@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: Participants and the postoperative outcomes assessor will be blinded to group allocation. The anesthesiologist performing the block procedure will not take part in postoperative data collection or outcome assessment.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: July 6, 2026
• First Posted: July 10, 2026
• Study Start: July 10, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 2, 2026
• Last Updated: July 30, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)