Comparative Study - Transseptal Suture Technique Verses Anterior Nasal Packing After Septoplasty

NCT07745127 | Recruiting

• 1 other identifier: No.F.1-1/2015/ERB/SZABMU/1428
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to see the outcomes of the two techniques used after septoplasty in terms of postoperative nasal pain and nasal bleeding in the patients with deviated nasal septum of 18 to 50 years of age presented in a tertiary care hospital. The main questions it aims to answer are:

1. 1.any significant difference between the two techniques in terms of post operative nasal pain?
2. 2.any significant difference between the two techniques in terms of post operative nasal bleeding? Researchers will be comparing the outcomes of these two techniques while participants already admitted in ward will be examined on 1st postoperative day.

Conditions

Deviated Nasal Septum; Postoperative Nasal Pain; Postoperative Nasal Bleeding

Keywords

septoplasty; deviated nasal septum (DNS); postoperative nasal pain; postoperative nasal bleeding; anterior nasal packing; merocel; trans-septal suture; hemorrhage

Outcome Measures

Primary Outcomes (1)

• Post operative Nasal Pain

  This will be assessed using Visual Analog scale on first post operative day

  24 hours after surgery on first post operative day

Secondary Outcomes (1)

• Post operative nasal hemorrhage

  24 hours after surgery on first post operative day

Study Arms (2)

Group A = with anterior nasal packing postoperative septoplasty

ACTIVE COMPARATOR

Group A will consists of 30 participants which will have anterior nasal packing done postoperatively, after septoplasty.

Procedure: Anterior nasal packing

Group B = with trans-septal suture technique

ACTIVE COMPARATOR

Group B will have 30 participants which will have trans-septal suture technique performed in septoplasty.

Procedure: Trans-septal suture technique

Interventions

Trans-septal suture technique PROCEDURE

Trans-septal suture technique in septoplasty

Group B = with trans-septal suture technique

Anterior nasal packing PROCEDURE

ANP

Group A = with anterior nasal packing postoperative septoplasty

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• symptomatic deviated nasal septum
• years of age
• both male and female genders

You may not qualify if:

• history of previous nasal surgery
• presence of chronic rhinosinusitis with or without nasal polyposis
• pregnant females
• immunocompromised patients
• patients with pulmonary and/or cardiovascular disorders
• patients those who received steroidal or anticoagulant therapy within last 30 days.

Sponsors & Collaborators

• Ghazal Iftakhar: lead
• Pakistan Institute of Medical Sciences: collaborator

Study Sites (1)

Pakistan Institute of Medical Sciences (PIMS), Islamabad.

Islamabad, Fedral, 44080, Pakistan

RECRUITING

Related Publications (4)

• Wang D, Liu T, Liao C, Tang G, Tian T, Tian L. Is nasal septal suturing an alternative technique to nasal packing?: A protocol for systematic review and meta-analysis. Medicine (Baltimore). 2020 Dec 11;99(50):e23535. doi: 10.1097/MD.0000000000023535.

  PMID: 33327302 BACKGROUND

• Ivanova PP, Iliev G. Nasal Packing in Septal Surgery: A Narrative Review. Cureus. 2023 Mar 21;15(3):e36488. doi: 10.7759/cureus.36488. eCollection 2023 Mar.

  PMID: 37090361 BACKGROUND

• Alsaggaf ZH, Almadfaa AO, Marouf AA, Alfawaz KS, Niyazi RA, Ibrahim NK, Ajlan AM. Sinusitis and its association with deviated nasal septum at a tertiary hospital: A retrospective study. J Taibah Univ Med Sci. 2022 Jun 18;17(6):1065-1069. doi: 10.1016/j.jtumed.2022.06.001. eCollection 2022 Dec.

  PMID: 36212586 BACKGROUND

• Alghamdi FS, Albogami D, Alsurayhi AS, Alshibely AY, Alkaabi TH, Alqurashi LM, Alahdal AA, Saber AA, Almansouri OS. Nasal Septal Deviation: A Comprehensive Narrative Review. Cureus. 2022 Nov 10;14(11):e31317. doi: 10.7759/cureus.31317. eCollection 2022 Nov.

  PMID: 36514566 BACKGROUND

MeSH Terms

Conditions

Hemorrhage

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Dr. Altaf Hussain

  Pakisrtan Institute of Medical Sciences, Islamabad.

  STUDY CHAIR

Central Study Contacts

Ghazal Iftakhar

CONTACT

+92 3309869344; ghazaliftakhar@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: CoComparative Study - Transseptal Suture Technique Verses Anterior Nasal Packing After Septoplasty

Model Details: Randomized control trial

Study Record Dates

• First Submitted: July 30, 2026
• First Posted: August 4, 2026
• Study Start: May 14, 2026
• Primary Completion (Estimated): November 12, 2026
• Study Completion (Estimated): November 12, 2026
• Last Updated: August 4, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will share
• Shared Documents: ICF

Locations

PA (1)