NCT00957502

Brief Summary

This study is a prospective, limited-use evaluation of the ENTact™ Septal Stapler for tissue approximation utilizing staples with extended shelf life. The ENTact™ Septal Stapler will be used to approximate the mucoperichondrial flaps in all patients. Each treatment group will be implanted with product that has been aged for a specified amount of time.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2009

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2009

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

August 10, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 12, 2009

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2010

Completed
Last Updated

August 23, 2012

Status Verified

August 1, 2012

Enrollment Period

7 months

First QC Date

August 10, 2009

Last Update Submit

August 21, 2012

Conditions

Outcome Measures

Primary Outcomes (1)

  • Clinical performance of aged ENTact™ Septal Staples

    One week post op

Secondary Outcomes (2)

  • Clinical evaluation of gross tissue appearance at implantation site(s)

    One week post op

  • ENTact™ Septal Staple functionality based on maintained coaptation

    One week post op

Study Arms (2)

One year aged staples

EXPERIMENTAL

Subjects implanted with sterile staples aged to approximately one year.

Device: ENTact™ Septal Stapler

18 month aged staples

EXPERIMENTAL

Subjects implanted with sterile staples aged to approximately 18 months.

Device: ENTact™ Septal Stapler

Interventions

1 year aged septal staples

One year aged staples

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult patients, between the ages of 18 and 65 years, with a clinically significant deviation of the nasal septum.
  • Patient is able to provide a signed informed consent form.
  • Patient will agree to comply with all study related procedures.
  • Subject is not pregnant at this time by confirmation of one of the following:
  • subject is male,
  • subject not of child bearing age,
  • subject is surgically sterile,
  • subject is not pregnant per negative hCG test.
  • Subject does not plan on becoming pregnant and is not breast feeding during the course of the study.

You may not qualify if:

  • Patients who have had previous septoplasty
  • Patients with uncontrolled diabetes
  • Presence of infection at the study site
  • Subject is a:
  • smoker,
  • severe drug abuser,
  • severe alcohol abuser.
  • Patient with autoimmune disease deemed clinically significant by the Principal Investigator.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Good Samaritan Hospital

Cincinnati, Ohio, 45220, United States

Location

Study Officials

  • Thomas A Tami, MD

    Good Samaritan Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 10, 2009

First Posted

August 12, 2009

Study Start

July 1, 2009

Primary Completion

February 1, 2010

Study Completion

February 1, 2010

Last Updated

August 23, 2012

Record last verified: 2012-08

Locations