NCT07742657

Brief Summary

This is a decentralized (fully virtual), single-group, open-label, prospective clinical trial evaluating the effects of Super Liver Liquid Drops, a liquid botanical dietary supplement, on gut health, digestive comfort, energy levels, and overall well-being over 12 weeks. All 35 enrolled participants will self-administer 2 mL of Super Liver Liquid Drops daily (2 droppers filled to 1 mL each) in the morning with breakfast for the full 12-week intervention period. Participants will complete validated questionnaires and self-reported assessments at Baseline, Week 2, Week 4, Week 8, and Week 12 via the Citruslabs study platform. All study activities will be conducted remotely.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
35

participants targeted

Target at P25-P50 for not_applicable

Timeline
1mo left

Started Jun 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress61%
Jun 2026Sep 2026

Study Start

First participant enrolled

June 24, 2026

Completed
12 days until next milestone

First Submitted

Initial submission to the registry

July 6, 2026

Completed
28 days until next milestone

First Posted

Study publicly available on registry

August 3, 2026

Completed
29 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2026

Last Updated

August 3, 2026

Status Verified

July 1, 2026

Enrollment Period

2 months

First QC Date

July 6, 2026

Last Update Submit

July 28, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in Gastrointestinal Symptom Rating Scale (GSRS)

    Change from baseline to Week 12 in gastrointestinal symptom severity as assessed by the Gastrointestinal Symptom Rating Scale (GSRS). Higher scores indicate greater gastrointestinal symptom severity.

    Baseline to Week 12

Secondary Outcomes (6)

  • Change in Self-Reported Energy Level Score

    Baseline to Week 12

  • Change in Self-Reported Brain Fog Score

    Baseline to Week 12

  • Change in Self-Reported Mood Stability Score

    Baseline to Week 12

  • Change in Self-Reported Sleep Quality Score

    Baseline to Week 12

  • Change in Self-Reported Skin Clarity Score

    Baseline to Week 12

  • +1 more secondary outcomes

Study Arms (1)

Super Liver Arm

EXPERIMENTAL
Dietary Supplement: Super Liver

Interventions

Super LiverDIETARY_SUPPLEMENT

All 35 enrolled participants self-administer 2 mL of Super Liver Liquid Drops daily (2 droppers filled to 1 mL each), taken in the morning with breakfast, for 12 consecutive weeks.

Super Liver Arm

Eligibility Criteria

Age30 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Be male or female.
  • Be aged 30-65 years (inclusive) at the time of enrollment.
  • Over the past four weeks, has had concerns regarding low energy levels and at least two of the following: Bloating, Digestion, Irregular Bowel movements, Brain fog.
  • Anyone who is generally healthy - does not live with any uncontrolled chronic disease.
  • Willing and able to follow the study protocol as described.
  • Willing to maintain their current diet, exercise routine, and sleep patterns, for the duration of the trial.
  • If taking other over-the-counter supplements or herbal remedies is willing to maintain this routine without introducing any other new products for the study duration.
  • Resides in the United States.
  • Willing to follow the study protocol as described.

You may not qualify if:

  • Known allergy or sensitivity to any of the study product ingredients (milk thistle, dandelion, yellow dock, turmeric, ginger, chicory/inulin, berberine).
  • Known history of severe digestive disorders like acid reflux, Irritable Bowel Syndrome (IBS), Irritable Bowel Disease (IBD), Crohn's disease, or gastrointestinal tract surgeries.
  • Known history of gallbladder disease or bile duct obstruction.
  • Has a chronic health condition that could impact participation in this study, such as oncological or psychiatric disorders.
  • Has a planned surgery in the next 12 weeks.
  • Currently pregnant, breastfeeding, or planning to become pregnant during the study period.
  • Known history of substance abuse.
  • Currently, or was in the past 3 months, a smoker.
  • Currently participating in or planning to participate in another research study during the study period.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Citruslabs

Las Vegas, Nevada, 89118, United States

Location

MeSH Terms

Conditions

Mental FatigueSleep Initiation and Maintenance DisordersHalitosis

Condition Hierarchy (Ancestors)

FatigueSigns and SymptomsPathological Conditions, Signs and SymptomsBehavioral SymptomsBehaviorSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesMental DisordersSigns and Symptoms, Digestive

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 6, 2026

First Posted

August 3, 2026

Study Start

June 24, 2026

Primary Completion (Estimated)

September 1, 2026

Study Completion (Estimated)

September 1, 2026

Last Updated

August 3, 2026

Record last verified: 2026-07

Locations