Effects of Two Different Kinesiotaping Techniques in Carpal Tunnel Syndrome

NCT07742293 | Not Yet Recruiting

• 1 other identifier: Protocol ID: 984
• Study Type: interventional
• Target: 90
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to evaluate the clinical, functional, and ultrasonographic effects of two different kinesiotaping techniques added to a standard exercise and night splint program in the treatment of Carpal Tunnel Syndrome (CTS). Participants will be randomly assigned to one of three groups: the I-Strip kinesiotaping technique group, the Button Hole kinesiotaping technique group, or a control group receiving only standard therapy. The study will assess treatment outcomes over a 12-week period using high-resolution ultrasound (specifically median nerve cross-sectional area and flattening ratio) and clinical parameters to determine the most effective conservative management approach.

Conditions

Carpal Tunnel Syndrome

Keywords

Kinesiotaping; Ultrasonography; Median Nerve; Exercise Therapy

Outcome Measures

Primary Outcomes (2)

• Median Nerve Flattening Ratio (FR)

  Measurements will be taken at the pisiform bone level using resolution ultrasound.

  At baseline (T0), 3rd week (T1), and 12th week (T2)

• Median Nerve Cross-Sectional Area (CSA)

  Using high-resolution ultrasound, measurements will be taken in millimeters square (mm2) at the pisiform bone level.

  At baseline (T0), 3rd week (T1), and 12th week (T2)

Secondary Outcomes (5)

• Visual Analog Scale (VAS) for Pain (Rest and activity pain intensity, 0-10 cm)

  At baseline (T0), 3rd week (T1), and 12th week (T2)

• Visual Analog Scale (VAS) for Numbness/Paresthesia (Median nerve trajectory, 0-10 cm)

  At baseline (T0), 3rd week (T1), and 12th week (T2)

• Boston Carpal Tunnel Questionnaire (BCTQ) for Symptom Severity and Functional Status

  At baseline (T0), 3rd week (T1), and 12th week (T2)

• Douleur Neuropathique 4 (DN4) Questionnaire Score

  At baseline (T0), 3rd week (T1), and 12th week (T2)

• Jamar Dynamometer Grip Strength in Kilograms (kg)

  At baseline (T0), 3rd week (T1), and 12th week (T2)

Study Arms (3)

I-Strip Kinesiotaping Group

EXPERIMENTAL

Participants will receive the original I-Strip kinesiotaping technique combined with standard exercise and a night splint program.

Other: I-Strip Kinesiotaping and Standard Therapy; Other: Standard Exercise and Splint Therapy

Button Hole Kinesiotaping Group

EXPERIMENTAL

Participants will receive the Button Hole kinesiotaping technique combined with standard exercise and a night splint program.

Other: Button Hole Kinesiotaping and Standard Therapy; Other: Standard Exercise and Splint Therapy

Control Group

ACTIVE COMPARATOR

Participants will only receive a standard exercise and overnight splint program.

Other: Standard Exercise and Splint Therapy

Interventions

I-Strip Kinesiotaping and Standard Therapy OTHER

Application of the original I-Strip kinesiotaping technique combined with a standard program of tendon/nerve gliding exercises and a night splint for 12 weeks.

I-Strip Kinesiotaping Group

Button Hole Kinesiotaping and Standard Therapy OTHER

Application of the Button Hole kinesiotaping technique combined with a standard program of tendon/nerve gliding exercises and a night splint for 12 weeks.

Button Hole Kinesiotaping Group

Standard Exercise and Splint Therapy OTHER

Twelve weeks of tendon/nerve gliding exercises and night splinting.

Button Hole Kinesiotaping Group; Control Group; I-Strip Kinesiotaping Group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Being aged between 18 and 65 years.
• Willingness and ability to sign the informed consent form.
• Having symptoms of carpal tunnel syndrome (hand numbness, tingling, pain) for at least 3 months.
• Clinical diagnosis of mild-to-moderate carpal tunnel syndrome confirmed by physical examination (positive Phalen/Tinel tests) and a prior nerve conduction study (EMG).

You may not qualify if:

• Previous wrist or hand surgery.
• Severe carpal tunnel syndrome on EMG (evidence of thenar atrophy or severe motor loss).
• History of trauma, fracture in the wrist area, or anatomical anomalies affecting ultrasonography.
• Cervical radiculopathy, polyneuropathy, diabetic neuropathy, or other concomitant upper extremity entrapment neuropathies.
• Local corticosteroid injection to the carpal tunnel within the last 6 months.
• Pregnancy.
• Systemic corticosteroid use or inflammatory rheumatic diseases.
• Cognitive impairment or psychiatric illness preventing comprehension of questionnaire instructions.
• Lack of a prior EMG report upon admission to the outpatient clinic.

Sponsors & Collaborators

• Kayseri City Hospital: lead

MeSH Terms

Conditions

Carpal Tunnel Syndrome

Interventions

Standard of Care

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries

Intervention Hierarchy (Ancestors)

Quality Indicators, Health Care; Quality of Health Care; Health Services Administration; Health Care Quality, Access, and Evaluation

Central Study Contacts

Furkan Erdinc, MD

CONTACT

+905413216609; frkn.erdinc01@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Medical Doctor

Study Record Dates

• First Submitted: July 25, 2026
• First Posted: August 3, 2026
• Study Start: August 1, 2026
• Primary Completion (Estimated): February 1, 2027
• Study Completion (Estimated): March 1, 2027
• Last Updated: August 7, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF
• Time Frame: Beginning from the date of publication and extending for 3 years.
• Access Criteria: Researchers who provide a scientifically sound proposal and whose proposed use of data has been approved by the principal investigator. Requests can be directed to the corresponding author via email.