Active Cycle Of Breathing Technique And Pursed Lip Breathing in Moderate to Severe COPD Patients

NCT07742033 | Completed DMC

• 1 other identifier: UOL/IREB/25/12/0002
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Purpose of the Study Chronic Obstructive Pulmonary Disease (COPD) is a progressive, long-term lung condition that limits airflow and makes breathing difficult. People with COPD frequently experience shortness of breath, chronic coughing, and mucus buildup, which can severely impact their daily activities and overall quality of life. While medications are commonly used, non drug therapies like specialized breathing exercises are becoming vital tools to help relieve symptoms. The purpose of this study is to compare two popular breathing techniques the Active Cycle of Breathing Technique (ACBT) and Pursed-Lip Breathing (PLB) to determine which method is more effective at improving lung function, reducing breathlessness, and enhancing the overall quality of life for individuals living with moderate to severe COPD. Study Plan and Methods This study is a randomized controlled trial lasting approximately 8 to 10 months. A total of 40 eligible participants (both men and women aged 40 to 55) will be recruited and randomly split into two equal groups: Group A (Active Cycle Breathing): Participants will practice ACBT, which combines relaxed breathing, deep chest-expanding breaths, and a specialized coughing technique ("huffing") to clear trapped mucus from the lungs Group B (Pursed-Lip Breathing): Participants will practice PLB, a technique where they inhale slowly through the nose and exhale gently through puckered lips (like blowing out a candle) to slow down breathing and improve ventilation Both groups will receive their assigned breathing exercise alongside standard medical care and a baseline postural drainage treatment. Exercises will be performed in 15-to-20-minute sessions, twice a day, for a total of 8 weeks. Expected Outcomes Researchers will evaluate participants before and after the 8-week program using standard lung function tests (spirometry), breathlessness questionnaires, and quality-of-life assessments. The study expects both techniques to offer relief, but aims to identify if one method provides superior evidence-based benefits. The ultimate goal is to help physical therapists and doctors design more effective, personalized pulmonary rehabilitation programs for COPD patients.

Conditions

Chronic Obstructive Pulmonary Disease (COPD); Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Keywords

Chronic Obstructive Pulmonary Disease (COPD),; Active Cycle of Breathing Technique (ACBT); Pursed Lip Breathing (PLB); Pulmonary Function; Pakistan

Outcome Measures

Primary Outcomes (1)

• orced Expiratory Volume in 1 second (FEV1)

  Baseline and post-intervention at 8 weeks

Secondary Outcomes (1)

• Pulmonary Function Test (FEV1/FVC Ratio)

  Baseline and post-intervention at 8 weeks

Study Arms (2)

Group A: Active Cycle of Breathing Technique (ACBT)

EXPERIMENTAL

For Arm 1 (Group A), enter this text into the description field: Active Cycle of Breathing Technique (ACBT) group. Participants in this arm will perform the Active Cycle of Breathing Technique, which combines three phases: breathing control (relaxed breathing), thoracic expansion (deep breaths), and the forced expiratory technique ("huffing") to mobilize and clear mucus from the lungs. The intervention will be administered in 2 sessions per day for a total duration of 8 weeks. Each session will last approximately 15 to 20 minutes. Participants will also receive standard COPD medical care and medication, alongside standard baseline postural drainage.

Other: Active Cycle of Breathing Technique (ACBT)

Group B: Pursed Lip Breathing Technique (PLB)

EXPERIMENTAL

Pursed Lip Breathing (PLB) group. Participants in this arm will perform Pursed Lip Breathing, a technique where they slowly inhale through the nose for 2 counts and gently exhale through puckered lips for 4 or more counts to slow breathing and improve ventilation. The intervention will be administered in 2 sessions per day for a total duration of 8 weeks. Each session will last approximately 15 to 20 minutes. Participants will also receive standard COPD medical care and medication, alongside standard baseline postural drainage.

Other: Pursed Lip Breathing (PLB)

Interventions

Active Cycle of Breathing Technique (ACBT) OTHER

The intervention consists of the Active Cycle of Breathing Technique (ACBT), a flexible regimen of breathing exercises designed to clear excess secretions from the lungs. It will be performed in 3 distinct phases: 1) Breathing Control (relaxed, gentle breathing to calm the airways), 2) Thoracic Expansion (deep, controlled breaths to expand the chest and loosen mucus), and 3) Forced Expiratory Technique/FET (using "huffing" to mobilize and clear mucus). Participants will perform 2 sessions a day, lasting 15-20 minutes per session, for a total of 8 weeks. All sessions will be conducted under standard baseline postural drainage alongside standard medical care.

Group A: Active Cycle of Breathing Technique (ACBT)

Pursed Lip Breathing (PLB) OTHER

The intervention consists of the Pursed Lip Breathing (PLB) technique, a breathing exercise aimed at reducing breathlessness and improving ventilation efficiency. Participants are trained to slowly inhale through the nose for 2 counts (allowing the belly to expand) and gently exhale through puckered lips for 4 or more counts without forcing the air out. Participants will perform 2 sessions a day, lasting 15-20 minutes per session, for a total of 8 weeks. All sessions will be conducted under standard baseline postural drainage alongside standard medical care.

Group B: Pursed Lip Breathing Technique (PLB)

Eligibility Criteria

• Age: 40 Years - 55 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Both genders.
• Subjects with the 40-55 age years.
• Diagnosed with COPD
• Subjects who are on regular treatment
• Subjects who are conscious and cooperative
• Subjects who can understand and follow instruction

You may not qualify if:

• Patients with recent abdominal, and thoracic surgery.
• Patients with any Disability; Physical or Mental.
• Patients with unstable angina, advanced congestive heart failure, or severe pulmonary hypertension, because altered intrathoracic pressures during forced expirations strain the heart.
• Patients with advanced kyphoscoliosis or severe pectus excavatum, as baseline structural restrictions prevent optimal diaphragmatic excursion and chest wall expansion.
• Patients presenting with severe resting hypoxemia or highly volatile blood oxygen values at baseline that require continuous emergency clinical monitoring.
• Patients who have experienced a sudden worsening or an acute clinical crash within the past 4 weeks, as the forced expiratory components (such as huffing) involved in active airway clearance can severely exacerbate active bronchospasms.

Sponsors & Collaborators

• University of Lahore: lead
• University of Lahore Hospital (ULH): collaborator

Study Sites (1)

Dr.Sidra Faisal

Lahore, Punjab Province, Pakistan

Location

Related Links

• Related Info

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 14, 2026
• First Posted: August 3, 2026
• Study Start: January 11, 2025
• Primary Completion: February 20, 2026
• Study Completion: June 30, 2026
• Last Updated: August 3, 2026

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)