Patient and Provider Perspectives on Genetic Risk Profiling

NCT07741929 | Recruiting

• 1 other identifier: CCR6285
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

A qualitative interview study exploring the patient and provider perspectives on the clinical utility of genetic risk profiling in routine clinical practice. The findings from the study may contribute towards future research and informing clinical practice.

Conditions

Prostate Cancer

Keywords

Patients; Providers; Genetic Risk Profiling; Prostate Cancer; Clinical Utility; Perspectives

Outcome Measures

Primary Outcomes (1)

• Data pertaining to the experiences and perspectives of healthcare providers and patients regarding the clinical utility of genetic risk profiling in routine clinical practice, using a qualitative (interview) thematic analysis approach.

  The study findings will provide data pertaining to the current experiences, perspectives, benefits, limitations and challenges patients and providers encounter when receiving and delivering genetic risk profiling results. The findings can help to highlight areas of concern which need to be addressed, improved and/or implemented prior to clinical implementation of genetic risk profiling into routine clinical care. The findings can also identify the educational, clinical and/or support needs and may also highlight aspects of clinical care which need to be improved or established (e.g. screening guidelines, resources, upskilled workforce) prior to the integration of genetic risk profiling into routine clinical practice. This will ensure that genetic risk profiling is relevant and feasible in terms of improving the clinical care and health seeking behaviours of patients.

  January 2026 to August 2027

Study Arms (2)

Patient participants

Diverse cohort of patients who have undergone genetic risk profiling and have received their results

Other: Qualitative interview

Provider participants

Healthcare providers who have delivered genetic risk profiling results to patients

Other: Qualitative interview

Interventions

Qualitative interview OTHER

Interview of participants to gain perspectives and experiences

Patient participants; Provider participants

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients who have undergone and received a genetic risk profiling result for prostate cancer and healthcare providers who have delivered a genetic risk profiling result for prostate cancer

You may qualify if:

• Individuals assigned male at birth who are aged 18 and over and who have capacity to consent
• Patients who have undergone genetic risk profiling for prostate cancer and have received their results
• Individuals from diverse backgrounds (age, ethnicity, risk status, etc)
• Healthcare providers who have delivered a genetic risk profiling result for prostate cancer

You may not qualify if:

• Individuals who lack capacity to consent
• Individuals deemed unsuitable to recruit based on their poor performance status or current medical condition

Sponsors & Collaborators

• Royal Marsden NHS Foundation Trust: lead
• Institute of Cancer Research, United Kingdom: collaborator

Study Sites (1)

The Royal Marsden Hospital (Sutton and Chelsea)

London, SM2 5PT, United Kingdom

RECRUITING

MeSH Terms

Conditions

Prostatic Neoplasms

Condition Hierarchy (Ancestors)

Genital Neoplasms, Male; Urogenital Neoplasms; Neoplasms by Site; Neoplasms; Genital Diseases, Male; Genital Diseases; Urogenital Diseases; Prostatic Diseases; Male Urogenital Diseases

Study Officials

• Elizabeth Bancroft, RN PhD

  The Royal Marsden NHS Foundation Trust / The Institute of Cancer Research

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Tarryn Shaw, MSc

CONTACT

020 8661 3375; tarryn.shaw@rmh.nhs.uk

Elizabeth Bancroft, RN PhD

CONTACT

02087224483; elizabeth.bancroft@rmh.nhs.uk

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 14, 2026
• First Posted: August 3, 2026
• Study Start: May 1, 2026
• Primary Completion (Estimated): August 31, 2027
• Study Completion (Estimated): August 31, 2027
• Last Updated: August 3, 2026

Record last verified: 2026-07

Locations

GB (1)