Investigating a Mediation Model of Emotion Regulation and Psychological Resilience in Relationship Between Mindfulness and Negative Emotions Among College Students in Guangzhou

NCT07741422 | Completed DMC

• 1 other identifier: USM/JEPeM/KK/25090763
• Study Type: interventional
• Target: 135
• Locations: 1 country
• Sites: 1

Brief Summary

This study examines whether a four-week mindfulness-based intervention can reduce depression, anxiety, and stress among college students in Guangzhou, China. It also investigates whether changes in mindfulness, emotion regulation, and psychological resilience may help explain the effects of the intervention. Eligible participants will be randomly assigned to either a mindfulness intervention group or a health education control group. The intervention group will receive weekly mindfulness-based training and complete brief daily mindfulness practice, while the control group will receive health education sessions. Participants will complete questionnaires assessing mindfulness, cognitive reappraisal, expressive suppression, psychological resilience, depression, anxiety, and stress before and after the intervention and at follow-up.

Conditions

Depression; Anxiety; Stress

Keywords

Mindfulness; Mindfulness-Based Intervention; Emotion Regulation; Cognitive Reappraisal; Expressive Suppression; Psychological Resilience; College Students; Negative Emotions

Outcome Measures

Primary Outcomes (1)

• Change in Depression, Anxiety, and Stress Symptoms Assessed by the Depression Anxiety Stress Scales-21

  Depression, anxiety, and stress symptoms will be assessed using the 21-item Depression Anxiety Stress Scales (DASS-21). The scale contains three 7-item subscales measuring depression, anxiety, and stress. Each item is rated from 0 to 3. Subscale scores are summed and multiplied by two, with higher scores indicating greater symptom severity.

  Baseline and immediately after the 4-week intervention

Secondary Outcomes (4)

• Change in Mindfulness Assessed by the 15-Item Five Facet Mindfulness Questionnaire

  Baseline and immediately after the 4-week intervention

• Change in Cognitive Reappraisal Assessed by the Emotion Regulation Questionnaire

  Baseline and immediately after the 4-week intervention

• Change in Expressive Suppression Assessed by the Emotion Regulation Questionnaire

  Baseline and immediately after the 4-week intervention

• Change in Psychological Resilience Assessed by the Connor-Davidson Resilience Scale

  Baseline and immediately after the 4-week intervention

Study Arms (2)

Mindfulness-Based Intervention

EXPERIMENTAL

Participants in this arm will receive a four-week mindfulness-based intervention. The program includes weekly group sessions and brief daily home practice focusing on mindful breathing, body awareness, mindful movement, and awareness of thoughts and emotions.

Behavioral: Mindfulness-Based Intervention

Health Education Control Group

ACTIVE COMPARATOR

Participants in this arm will receive health education sessions of comparable frequency and duration, focusing on stress management, emotional well-being, and healthy lifestyle practices.

Behavioral: Health Education

Interventions

Mindfulness-Based Intervention BEHAVIORAL

Participants received a four-week mindfulness-based intervention consisting of one 90-minute group session per week and approximately 10 minutes of daily home practice. The program included mindful breathing, body scan practice, mindful movement, awareness of thoughts and emotions, and exercises for responding to stress. The intervention was adapted from mindfulness-based stress reduction principles for college students.

Mindfulness-Based Intervention

Health Education BEHAVIORAL

Participants received a four-week health education program consisting of one group session per week. The sessions addressed general stress management, emotional well-being, healthy lifestyle practices, and other health-related topics. The program did not include mindfulness meditation or formal mindfulness practice.

Health Education Control Group

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• \- Full-time college students enrolled at a participating institution in Guangzhou, China.
• Aged 18 to 30 years.
• Able to read and understand Chinese.
• Willing to provide informed consent.
• Completed the initial questionnaire assessment.
• Reported at least mild symptoms of depression, anxiety, or stress on at least one subscale of the Depression Anxiety Stress Scales-21.
• Willing and able to participate in the four-week intervention and complete the required assessm

You may not qualify if:

• \- Currently receiving psychiatric or psychological treatment.
• Diagnosed with a severe mental disorder or other severe psychopathology that could interfere with participation.
• At acute risk of suicide or self-harm.
• Currently participating in another psychological or mental health intervention.
• Currently engaging in regular mindfulness meditation or enrolled in another mindfulness-based program.
• Pregnant.
• Having a physical or medical condition that prevents participation in the intervention activities.
• Unable to complete the intervention or study assessments.

Sponsors & Collaborators

• Universiti Sains Malaysia: lead

Study Sites (1)

Guangzhou City Construction College

Guangzhou, Guangdong, 715517, China

Location

MeSH Terms

Conditions

Depression; Anxiety Disorders; Emotional Regulation

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior; Mental Disorders; Self-Control; Social Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PHD

Study Record Dates

• First Submitted: July 27, 2026
• First Posted: August 3, 2026
• Study Start: April 1, 2026
• Primary Completion: April 20, 2026
• Study Completion: May 20, 2026
• Last Updated: August 3, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)