NCT07741214

Brief Summary

Patients with obstructed flow due to BPH will be enrolled into 2 groups, group will undergo TURP and the other group will undergo Low power HOLEP

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
15mo left

Started Aug 2026

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress1%
Aug 2026Nov 2027

First Submitted

Initial submission to the registry

June 26, 2026

Completed
1 month until next milestone

Study Start

First participant enrolled

August 1, 2026

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 3, 2026

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2027

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2027

Last Updated

August 3, 2026

Status Verified

July 1, 2026

Enrollment Period

1 year

First QC Date

June 26, 2026

Last Update Submit

July 28, 2026

Conditions

BPH With Urinary ObstructionProstatic Hyperplasia

Keywords

Low power HOLEPTURPHOLEPBPH

Outcome Measures

Primary Outcomes (1)

  • Change in The International Prostate Symptom Score (IPSS)

    The International Prostate Symptom Score (IPSS) can be utilized to measure the severity of lower urinary tract symptoms. It is a validated, reproducible scoring system to assess disease severity and response to therapy. The IPSS is made up of 7 questions related to voiding symptoms. A score of 0 to 7 indicates mild symptoms, 8 to 19 indicates moderate symptoms and 20 to 35 indicates severe symptoms.

    6 months

Study Arms (2)

TURP

ACTIVE COMPARATOR
Procedure: low power HOLEPProcedure: TURP

LOW POWER HOLEP

ACTIVE COMPARATOR

patients who will undergo low power HOLEP

Procedure: low power HOLEPProcedure: TURP

Interventions

low power HOLEPPROCEDURE

Patients who will undergo transurethral resection of the prostate

LOW POWER HOLEPTURP
TURPPROCEDURE

Patients who will undergo transurethral resection of the prostate

LOW POWER HOLEPTURP

Eligibility Criteria

Age50 Years+
Sexmale(Gender-based eligibility)
Gender Eligibility Detailsmales with obstructed flow due to BPH
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • \- mens with LUTS due to obstructed prostate

You may not qualify if:

  • stone bladder bladder cancer prostate cancer

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mohamed Fawzy Salman

Cairo, Egypt

Location

MeSH Terms

Conditions

Prostatic Hyperplasia

Interventions

Transurethral Resection of Prostate

Condition Hierarchy (Ancestors)

Prostatic DiseasesGenital Diseases, MaleGenital DiseasesUrogenital DiseasesMale Urogenital Diseases

Intervention Hierarchy (Ancestors)

ProstatectomyUrologic Surgical Procedures, MaleUrologic Surgical ProceduresUrogenital Surgical ProceduresSurgical Procedures, Operative

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer of urology

Study Record Dates

First Submitted

June 26, 2026

First Posted

August 3, 2026

Study Start

August 1, 2026

Primary Completion (Estimated)

August 1, 2027

Study Completion (Estimated)

November 1, 2027

Last Updated

August 3, 2026

Record last verified: 2026-07

Locations

EG(1)