A Study to Evaluate the Effects of a Supplement on Mucus Clearance and Respiratory Symptoms

NCT07740746 | Completed

• 1 other identifier: 20752
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

This is a randomized, triple-blind, placebo-controlled clinical trial evaluating the effects of the BetterLungs Mullein + Chlorophyll supplement on mucus clearance and respiratory symptoms over 60 days. One hundred adult participants experiencing chest mucus build-up, difficulty clearing mucus, breathlessness, and low energy levels will be enrolled and randomized to either the active supplement or a matched placebo. Participants will take their assigned product once daily in the morning mixed with water and will complete self-reported questionnaires at Baseline, Day 20, Day 40, and Day 60.

Conditions

Mucus Clearance; Respiratory Symptoms; Breathlessness; Chest Mucus Accumulation; Low Energy Levels

Outcome Measures

Primary Outcomes (2)

• Change in mucus clearance

  Self-reported change in mucus clearance assessed via questionnaire

  Baseline, Day 20, Day 40, and Day 60

• Change in respiratory symptoms

  Self-reported change in respiratory symptoms assessed via questionnaire

  Baseline, Day 20, Day 40, and Day 60

Secondary Outcomes (6)

• Change in perceived mucus clearance

  Baseline, Day 20, Day 40, and Day 60

• Change in energy levels

  Baseline, Day 20, Day 40, and Day 60

• Change in shortness of breath

  Baseline, Day 20, Day 40, and Day 60

• Change in breathing-related anxiety

  Baseline, Day 20, Day 40, and Day 60

• Change in ease of breathing

  Baseline, Day 20, Day 40, and Day 60

Study Arms (2)

BetterLungs Mullein

EXPERIMENTAL

Dietary Supplement: BetterLungs

Placebo

PLACEBO COMPARATOR

Dietary Supplement: Placebo

Interventions

BetterLungs DIETARY_SUPPLEMENT

50 participants receive the BetterLungs Mullein + Chlorophyll supplement (ingredients: mullein leaf, chlorophyll, vegetable glycerin, purified water) taken once daily in the morning with the first meal of the day; 2 mL (two full droppers) mixed with 8 ounces of water for 60 days

BetterLungs Mullein

Placebo DIETARY_SUPPLEMENT

50 participants receive a matched placebo product (ingredients: moss coloring jungle green color, violet color, spirulina, vegetable glycerin, purified water) taken once daily in the morning with the first meal of the day; 2 mL (two full droppers) mixed with 8 ounces of water for 60 days; the taste and appearance of the placebo are matched to the active product

Placebo

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Be male or female
• Be aged 18+
• Anyone experiencing issues regarding all of the following over the past three months: a build-up of chest mucus, difficulty clearing chest mucus, breathlessness, and low energy levels
• Anyone who is generally healthy - does not live with any uncontrolled chronic disease
• Willing to refrain from taking any products, prescription medications, or supplements that target lung health, mucus, and energy levels during the test period
• Willing to maintain your current diet, sleep schedule, and activity level for the duration of the study
• Resides in the United States
• Not currently partaking in another research study and will not be partaking in any other research study for the next 60 days and at any point during this study's duration
• If currently taking prescription medication are willing to discuss it with their physician before participating in this study

You may not qualify if:

• Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including kidney disease, diabetes, cancer, mental health disorders, history of serious illness in the last three months, history of substance abuse, or planned surgery during the study period
• Anyone who drinks heavily (i.e. 8 or more alcoholic drinks per week for women or 15 or more alcoholic drinks per week for men)
• Anyone with a copper sensitivity disorder (such as Wilson's disease or copper metabolism disorders)
• Anyone with kidney disease
• Anyone with diabetes
• Anyone with any known allergies or hypersensitivities to any supplement product ingredients
• Anyone who is currently pregnant, trying to conceive, or breastfeeding

Sponsors & Collaborators

• The Better Brand Inc.: lead
• Citruslabs: collaborator

Study Sites (1)

Citruslabs

Las Vegas, Nevada, 89118, United States

Location

MeSH Terms

Conditions

Signs and Symptoms, Respiratory; Dyspnea

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Respiration Disorders; Respiratory Tract Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 28, 2026
• First Posted: August 3, 2026
• Study Start: April 22, 2025
• Primary Completion: August 30, 2025
• Study Completion: August 30, 2025
• Last Updated: August 3, 2026

Record last verified: 2026-07

Locations

US (1)