Intensive Inpatient Trauma-Focused Cognitive Behavioral Therapy (II-TF-CBT) for Adolescents With PTSD Following Sexual Abuse

NCT07732335 | Completed

• 1 other identifier: TABED 1/808/2024
• Study Type: observational
• Target: 75
• Locations: 1 country
• Sites: 1

Brief Summary

This study looks at a treatment program for children and teens who have post-traumatic stress disorder (PTSD) after sexual abuse. The program is called II-TF-CBT. It is a special version of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT), a type of cognitive behavioral therapy that helps people process trauma. II-TF-CBT is used with patients who stay in the hospital during treatment. Researchers want to know if II-TF-CBT helps young patients recover as well as, or better than, standard outpatient treatment. Outpatient treatment means patients visit the clinic but do not stay overnight. The study compares two groups. One group of 42 patients received II-TF-CBT during a hospital stay. The other group of 33 patients received standard outpatient treatment. Patients needing inpatient care were placed on an admission waiting list and admitted as their turn came; the remaining patients continued outpatient follow-up. Group placement therefore happened naturally, without researcher intervention. Doctors measured each patient's PTSD symptoms and related problems before treatment, after treatment, and at a follow-up visit. This will help show whether inpatient TF-CBT-based care can help children and teens recover from trauma.

Conditions

Post-Traumatic Stress Disorder, PTSD; Child Sexual Abuse

Outcome Measures

Primary Outcomes (1)

• Change in Clinical Global Impression-Severity (CGI-S) Score

  The CGI-S is a clinician-rated scale assessing the overall severity of the patient's psychiatric symptoms on a 7-point scale, ranging from 1 (normal, not at all ill) to 7 (among the most extremely ill patients). Change in CGI-S score over the course of treatment reflects overall clinical improvement in trauma-related symptom severity. Scores range from 1 (normal, not at all ill) to 7 (among the most extremely ill patients). Higher scores indicate greater illness severity (worse outcome).

  Baseline, Week 2, and Week 4)

Secondary Outcomes (3)

• Change in Children's Depression Inventory (CDI) Total Score

  Baseline, Week 2, and Week 4

• Change in Screen for Child Anxiety Related Emotional Disorders (SCARED) Total Score

  Baseline, Week 2, and Week 4

• Change in National Stressful Events Survey PTSD Short Scale (Child Version) (NSESSS) Total Score

  Baseline, Week 2, and Week 4

Study Arms (2)

II-TF-CBT (Inpatient)

Patients hospitalized for treatment who received the II-TF-CBT protocol - an inpatient adaptation of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) that includes an added Intake phase prior to the standard TF-CBT components. Patients were admitted from a waiting list of children and adolescents requiring inpatient care for post-traumatic stress disorder (PTSD) following sexual abuse. Group assignment occurred naturally based on bed availability and admission order, not by researcher allocation. N=42.

Behavioral: II-TF-CBT

Outpatient Follow-up (Control)

Patients who continued standard outpatient treatment for PTSD following sexual abuse, without hospitalization. These patients remained on outpatient follow-up because they did not require or were not admitted for inpatient care. Group assignment occurred naturally based on clinical need, not by researcher allocation. N=33.

Interventions

II-TF-CBT BEHAVIORAL

An inpatient adaptation of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) for children and adolescents with post-traumatic stress disorder following sexual abuse. The protocol follows the standard TF-CBT components (psychoeducation, relaxation, affect regulation, cognitive coping, trauma narrative, in vivo mastery, conjoint sessions, and safety enhancement), delivered during inpatient hospitalization.

II-TF-CBT (Inpatient)

Eligibility Criteria

• Age: 11 Years - 17 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

'The study population consists of children and adolescents aged 11-17 years diagnosed with post-traumatic stress disorder (PTSD) according to DSM-5 criteria following sexual abuse, presenting to the inpatient and outpatient services of our clinic. Patients were enrolled over an 18-month period following ethics committee approval. Those clinically prioritized for hospitalization received inpatient treatment with the II-TF-CBT protocol; those with a similar clinical presentation who were awaiting inpatient admission continued outpatient follow-up during this period and formed the control group.'

You may qualify if:

• Age 11-17 years.
• Diagnosis of post-traumatic stress disorder (PTSD) according to DSM-5 criteria following sexual abuse.
• Admitted for inpatient treatment in the hospital's child and adolescent psychiatry inpatient unit within the 18-month enrollment period (II-TF-CBT group), or placed on the inpatient admission waiting list and followed in the outpatient clinic during the same period (outpatient control group).
• Patients meeting all eligibility criteria during the enrollment period were included.
• Assignment to the inpatient or outpatient control group was determined by clinical prioritization and admission order rather than by investigators.

You may not qualify if:

• Age younger than 11 years or older than 17 years.
• Refusal to participate in the study.
• Schizophrenia or another active psychotic disorder.
• Current manic episode.
• Intellectual disability.
• Pervasive developmental disorder.

Sponsors & Collaborators

• Ankara City Hospital Bilkent: lead

Study Sites (1)

Ankara Yenimahalle Training and Research Hospital

Ankara, Ankara, 06370, Turkey (Türkiye)

Location

Related Publications (1)

• Tural Hesapcioglu S, Dabak S, Aburşu H, Ceylan MF. Intensive Inpatient Trauma-Focused Cognitive Behavioral Therapy (II-TF-CBT) for Child and Adolescent Survivors of Sexual Trauma in Psychiatric Inpatient Care. Ann Clin Psychiatry. 2026;37(3):113-126.

  BACKGROUND

MeSH Terms

Conditions

Combat Disorders

Condition Hierarchy (Ancestors)

Stress Disorders, Traumatic; Trauma and Stressor Related Disorders; Mental Disorders

Study Officials

• Sevda Dabak, MD

  Ankara City Hospital Bilkent

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident Physician, Child and Adolescent Psychiatry

Study Record Dates

• First Submitted: July 24, 2026
• First Posted: July 28, 2026
• Study Start: January 5, 2025
• Primary Completion: June 10, 2026
• Study Completion: June 27, 2026
• Last Updated: July 30, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)