Follow-Up Study on Children Exposed to Trauma

NCT06975852 | Recruiting

• 1 other identifier: 2025/156
• Study Type: observational
• Target: 210
• Locations: 1 country
• Sites: 1

Brief Summary

As far as it is known, there is no longitudinal study in Turkey investigating the follow-up and treatment of children and adolescents exposed to trauma. This study is planned to reassess children and adolescents with trauma exposure who were evaluated in Istanbul Faculty of Medicine Child Psychiatry outpatient clinic as part of a thesis study one year ago (January-April 2024) and to examine how many of them continue to meet the criteria for Post-Traumatic Stress Disorder (PTSD), how many receive a diagnosis of Complex Post-Traumatic Stress Disorder (CPTSD), and which factors are associated with these outcomes. In this way, it is aimed to contribute to the literature on the long-term effects of trauma exposure. Additionally, since there is no scale in our country that assesses the diagnosis of CPTSD in children, the study also aims to translate the Child and Adolescent Trauma Screen Scale - 2 (CATS-2) into Turkish and examine its psychometric properties.

Conditions

Post-traumatic Stress Disorder (PTSD); Complex Post-Traumatic Stress Disorder (CPTSD)

Outcome Measures

Primary Outcomes (3)

• Prevalence of PTSD and Complex PTSD in Children and Adolescents Exposed to Trauma

  This study aims to investigate the prevalence of PTSD and CPTSD diagnoses one year after the initial assessment of trauma-exposed children and adolescents evaluated in our outpatient clinic between January and April 2024 as part of a thesis study.

  Baseline

• Factors Associated with the Diagnosis of PTSD and Complex PTSD

  We aim to investigate the correlations between PTSD, CPTSD diagnoses and various clinical measures, such as the child's PTSD symptom severity assessed by the UCLA RI-5, the child's PACE score, the parent's ACE and PACE scores, and the severity of parental anxiety and depression.

  Baseline

• Adaptation of the Child and Adolescent Trauma Screen - 2 into Turkish, Evaluation of Its Psychometric Properties

  Given the absence of an existing instrument to assess CPTSD in children in Turkey, this study also aims to translate the Child and Adolescent Trauma Screen - 2 (CATS-2) into Turkish and to evaluate its psychometric properties. The results of both the self-report and caregiver-report versions of the Turkish CATS-2, completed by children/adolescents and their parents respectively, will be compared with PTSD and CPTSD diagnoses obtained through a clinician-administered ICD-11-based clinical interview, as well as with the results of the UCLA PTSD Reaction Index for DSM-5 (RI-5).

  Baseline

Eligibility Criteria

• Age: 7 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients applying to the Child and Adolescent Psychiatry outpatient clinic of Istanbul Faculty of Medicine

You may qualify if:

• Children-adolescents who were exposed to at least one traumatic event and who were evaluated within the scope of the thesis study one year ago (January-April 2024),
• Children and adolescents aged 7-18,
• Children and/or parents with adequate literacy and Turkish language skills.

You may not qualify if:

• The presence of psychotic/manic symptoms in the child or parent during the interview or any condition that makes the interview and assessment impossible (e.g., mental or developmental condition or a different communication language),
• The child or parent refusing to participate in the study,
• The presence of autism spectrum disorder or intellectual disability at a severity that prevents assessment.

Sponsors & Collaborators

• Istanbul University: lead

Study Sites (1)

Istanbul Faculty of Medicine

Istanbul, Fatih, 34116, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Stress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Stress Disorders, Traumatic; Trauma and Stressor Related Disorders; Mental Disorders

Study Officials

• Abdurrahman C Orengul, Associate Professor

  Istanbul Faculty of Medicine, Child and Adolescent Psychiatry Department

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Beyza N Karal, MD

CONTACT

+9002124142000; beyzakaral@istanbul.edu.tr

Study Design

• Study Type: observational
• Observational Model: FAMILY BASED
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Assistant, MD

Study Record Dates

• First Submitted: April 25, 2025
• First Posted: May 16, 2025
• Study Start: February 17, 2025
• Primary Completion: July 18, 2025
• Study Completion: August 15, 2025
• Last Updated: May 16, 2025

Record last verified: 2025-05

Locations

TU (1)