Factors Affecting Participation in Daily Living in Stroke: Roles of Spasticity, Upper Extremity, Cognition and Function

NCT07723898 | Completed

• 1 other identifier: 60116787-020/50461
• Study Type: observational
• Target: 49
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to identify the factors affecting participation in daily living activities in stroke individuals and their interrelationships. Participation in daily living activities and related factors such as spasticity, upper extremity function, cognitive status, and functional status were assessed in individuals diagnosed with stroke. Hypothesis 1: Spasticity in stroke patients affects participation in daily living activities. Hypothesis 2: Upper extremity function in stroke patients affects participation in daily living activities. Hypothesis 3: Cognitive status in stroke patients affects participation in daily living activities. Hypothesis 4: Functional status in stroke patients affects participation in daily living activities.

Conditions

Stroke

Keywords

Stroke; Functionality; Walking; Activities of daily living; Participation

Outcome Measures

Primary Outcomes (1)

• Stroke Impact Scale (SIS) for assessment of participation in activities of daily living.

  The current SIS 3.0 is a revised version of the original SIS developed by Duncan et al. SIS 3.0 includes 59 items measuring eight domains, including strength, hand function, activities of daily living/instrumental activities of daily living, mobility, communication, emotion, memory/thinking, and participation, and one item assessing overall improvement. Items are rated using a Guttman-type scale with five response options. Patients are expected to complete the scale based on the difficulties they perceived last week. Scores of 5, 4, 3, 2, and 1 correspond to the options "not difficult at all," "very little difficult," "somewhat difficult," "very difficult," and "extremely difficult," respectively. Turkish validity and reliability were established by Hantal et al. in 2014, with Cronbachα values \> 0.70 and ICC 0.947 (0.947-0.999).

  The assessment was performed at least 3 months after the stroke.

Secondary Outcomes (10)

• Muscle tone assessment using the Modified Ashworth Scale (MAS).

  The assessment was performed at least 3 months after the stroke.

• Nine Hole Peg Test (NHPT) Assessment of upper extremity function

  The assessment was performed at least 3 months after the stroke.

• Assessment of upper extremity dexterity with Dexterity Questionnaire-24 (DextQ-24)

  The assessment was performed at least 3 months after the stroke.

• Montreal Cognitive Assessment (MoCA) for cognitive status assessment.

  The assessment was performed at least 3 months after the stroke.

• Fatigue assessment using the Fatigue Severity Scale (FSS).

  The assessment was performed at least 3 months after the stroke.

Study Arms (1)

Individuals with Stroke

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Individuals aged 18-80 diagnosed with stroke who were examined at the neurology outpatient clinic of Pamukkale University Hospitals.

You may qualify if:

• Having a stroke diagnosis.
• At least 3 months must have passed since the stroke.
• Not having hearing, vision, or speech problems that would affect the tests.
• Agreeing to participate in the study.
• Not having any non-stroke neurological or orthopedic disease that could affect function.

You may not qualify if:

• Having undergone musculoskeletal surgery on the upper extremity.
• Less than 3 months having passed since the stroke.
• Having hearing, vision, or speech problems severe enough to affect the tests.
• Having any non-stroke neurological or orthopedic disease that may affect function.

Sponsors & Collaborators

• Pamukkale University: lead

Study Sites (1)

Pamukkale University

Denizli, 20070, Turkey (Türkiye)

Location

Related Publications (11)

• Lin KC, Fu T, Wu CY, Hsieh YW, Chen CL, Lee PC. Psychometric comparisons of the Stroke Impact Scale 3.0 and Stroke-Specific Quality of Life Scale. Qual Life Res. 2010 Apr;19(3):435-43. doi: 10.1007/s11136-010-9597-5. Epub 2010 Feb 4.

  PMID: 20127418 BACKGROUND

• Duncan PW, Bode RK, Min Lai S, Perera S; Glycine Antagonist in Neuroprotection Americans Investigators. Rasch analysis of a new stroke-specific outcome scale: the Stroke Impact Scale. Arch Phys Med Rehabil. 2003 Jul;84(7):950-63. doi: 10.1016/s0003-9993(03)00035-2.

  PMID: 12881816 BACKGROUND

• Dönmez S., Dağ H., Kazandı M., Amniyosentez Öncesi Gebelerde Anksiyete ve Depresyon Risk Düzeylerinin Belirlenmesi. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi. 2012;4(3):255-259.

  BACKGROUND

• Charlson ME, Pompei P, Ales KL, MacKenzie CR. A newmethod of classifyingprognosticcomorbidity in longitudinalstudies: developmentandvalidation. J ChronicDis 1987;40:373-83.

  BACKGROUND

• Yalın H., İnme Sonrası Hastaların Fonksiyonel Durum, Engellilik Ve Yaşam Kaliteleri. Marmara Üniversitesi Sağlık Bilimleri Enstitüsü. İstanbul. 2011:42-43

  BACKGROUND

• Gencay-Can A, Can SS. Validation of theTurkishversion of thefatigueseverityscale in patientswithfibromyalgia. RheumatolInt. 2012;32(1):27- 31.

  BACKGROUND

• Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD. The fatigue severity scale. Application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol. 1989 Oct;46(10):1121-3. doi: 10.1001/archneur.1989.00520460115022.

  PMID: 2803071 BACKGROUND

• Çebi M. Mental durum için Kısa Test(STMS) ve MoCA'nınMMSE'ye karşı normal-Alzheimer Hastalığı-Hafif Kognitif Bozukluk Spektrumunda ayrım yeteneğinin karşılaştırılması. Yüksek lisans Tezi, İstanbul Üniversitesi Sağlık Bilimleri Enstitüsü, İstanbul, 2012:23

  BACKGROUND

• Vanbellingen T, Nyffeler T, Nef T, Kwakkel G, Bohlhalter S, van Wegen EE. Reliability and validity of a new dexterity questionnaire (DextQ-24) in Parkinson's disease. Parkinsonism Relat Disord. 2016 Dec;33:78-83. doi: 10.1016/j.parkreldis.2016.09.015. Epub 2016 Sep 15.

  PMID: 27663063 BACKGROUND

• Erhan B, Gündüz B. Spastisite. Tıbbi rehabilitasyon. 3. Baskı. İstanbul:Nobel Tıp Kitapevleri. 2015:565-573

  BACKGROUND

• Mathiowetz V, Weber K, Kashman N et al. Adultnormsfor nine hole peg test of fingerdexterity. TheOccupTher J. Res. 1983;5(1):25-38.

  BACKGROUND

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Nilüfer ÇETİŞLİ KORKMAZ, PT.PhD.Prof.

  Pamukkale University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physiotherapist, MSc

Study Record Dates

• First Submitted: July 16, 2026
• First Posted: July 23, 2026
• Study Start: September 5, 2020
• Primary Completion: April 30, 2022
• Study Completion: April 30, 2022
• Last Updated: July 23, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)