HFCWO in Children With Non-CF Bronchiectasis

NCT07722364 | Not Yet Recruiting DMC

• 1 other identifier: HFCWO and bronchectasis
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

the study will concentrate on the effect of High Frequency Chest Wall Oscillation compared to conventional pulmonary physiotherapy on children with non cystic fibrosis bronchiectasis

Conditions

Non Cystic Fibrosis Bronchiectasis

Keywords

HFCWO, cystic fibrosis, bronchiectasis

Outcome Measures

Primary Outcomes (3)

• Forced Expiratory Volume in 1 second (FEV1)

  Change in FEV1 measured by spirometry according to ATS/ERS guidelines

  Baseline and after 8 weeks of treatment

• Forced Vital Capacity (FVC)

  Change in FVC measured by spirometry according to ATS/ERS guidelines

  Baseline and after 6 months of treatment

• FEV1/FVC Ratio

  Change in FEV1/FVC ratio measured by spirometry according to ATS/ERS guidelines

  Baseline and after 6 months of treatment

Secondary Outcomes (1)

• Six-Minute Walk Distance (6MWD)

  Baseline and after 6 months of treatment

Study Arms (2)

children who will use HFCWO for 20 minutes, in addition to 10 minutes of the same conventional progr

EXPERIMENTAL

This group will include 30 children who will use HFCWO for 20 minutes, in addition to 10 minutes of the same conventional program of physiotherapy given to the control group. The frequency of treatment will be 5 sessions/week for three successive months for both groups for long term effect and daily for immediate effect.

Device: High Frequency Chest Wall Oscillation

children who will be treated by conventional physiotherapy program

ACTIVE COMPARATOR

Patients in this group will be 30 children who will be treated by conventional physiotherapy program directed towards improvement of pulmonary functions and quality of life.

Other: conventional physiotherapy program directed towards improvement of pulmonary functions and quality of life.

Interventions

High Frequency Chest Wall Oscillation DEVICE

High-frequency chest wall oscillation that applies external chest wall oscillations via an inflatable vest worn around the thoracic cage, increasing the air-liquid shear forces during expiration is believed to result in secretion mobilization. The product name that will be used is Air Way Clearness system; his model is PV-900/ PV-300/PV-100, made in China.

children who will use HFCWO for 20 minutes, in addition to 10 minutes of the same conventional progr

conventional physiotherapy program directed towards improvement of pulmonary functions and quality of life. OTHER

conventional physiotherapy program directed towards improvement of pulmonary functions and quality of life. Conventional physiotherapy that will be applied to the control group for 30 minutes will include: * Postural drainage according to accumulation of secretions for 10 minutes accompanied by percussion or vibration * Active cycle breathing technique (ACBT) for 10 minutes * Respiratory exercises for 10 minutes

children who will be treated by conventional physiotherapy program

Eligibility Criteria

• Age: 6 Years - 12 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Children with no cystic fibrosis bronchiectasis
• Both sexes
• Their ages ranges from 6-12 years
• After 48 hours of attack, if hemoptysis or fever not found

You may not qualify if:

• Osteoporosis (Calcium deficiency)
• Bleeding tendency
• Recent surgery of brain, eye, thoracic, or neck surgery
• Pneumothorax
• Cystic fibrosis bronchiectasis
• Pulmonary embolism
• Rib fracture

Sponsors & Collaborators

• Sphinx university: lead

Study Sites (1)

pediatric hospital, Assiut university

Asyut, Egypt

Location

MeSH Terms

Conditions

Cystic Fibrosis; Bronchiectasis

Interventions

Chest Wall Oscillation; Quality of Life

Condition Hierarchy (Ancestors)

Pancreatic Diseases; Digestive System Diseases; Lung Diseases; Respiratory Tract Diseases; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Infant, Newborn, Diseases; Bronchial Diseases

Intervention Hierarchy (Ancestors)

Respiratory Therapy; Therapeutics; Health Status; Demography; Epidemiologic Measurements; Public Health; Environment and Public Health

Central Study Contacts

Marwa elkawy, Msc

CONTACT

01030077626; marwa.elkawy@sphinx.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant lecturer, Faculty of Physical Therapy Sphinx University

Study Record Dates

• First Submitted: June 2, 2026
• First Posted: July 23, 2026
• Study Start: July 1, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): January 1, 2027
• Last Updated: July 28, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)