Building a Swiss Pain Registry: A National Framework for Acute and Chronic Pain Assessment

NCT07717762 | Not Yet Recruiting

• 1 other identifier: 2026-00636
• Study Type: observational
• Target: 500
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational registry is to systematically collect and analyse real-world clinical and patient-reported data in individuals receiving treatment for acute and chronic pain. The main questions it aims to answer are: How do pain intensity, functional status, and quality of life evolve over time in patients with acute and chronic pain? How are different routine clinical treatment approaches associated with patient-reported outcomes in real-world clinical practice? Participants already receiving standard care for pain management will have routine clinical data recorded as part of their treatment and will be asked to complete standardized questionnaires on pain intensity, functional status, and quality of life at multiple time points during treatment and follow-up. Data are collected using a secure electronic system and are pseudonymised prior to analysis in accordance with Swiss data protection regulations.

Conditions

Chronic Pain; Acute Pain

Outcome Measures

Primary Outcomes (2)

• Feasibility of baseline assessment

  Feasibility is defined as the proportion of eligible participants who complete the full multidomain digital baseline assessment across all predefined domains.

  Baseline (at enrollment)

• Data quality of baseline assessment

  Data quality will be evaluated by completeness of core variables of the multidomain digital baseline assessment (percentage of missing data at item and domain level).

  Baseline (at enrollment)

Secondary Outcomes (12)

• Pain intensity

  Baseline, 6, 12, 18, 24 months

• Pain interference

  Baseline, 6, 12, 18, 24 months

• Neuropathic pain screening

  Baseline, 6, 12, 18, 24 months

• Neuropathic pain symptom profile

  Baseline, 6, 12, 18, 24 months

• Functional disability

  Baseline, 6, 12, 18, 24 months

Other Outcomes (3)

• Post-intervention pain intensity and interference

  Approximately 1 week after intervention (post-intervention follow-up; variable depending on clinical trigger)

• Post-intervention side effects and adverse events

  Approximately 1 week after intervention (post-intervention follow-up; variable depending on clinical trigger)

• Post-intervention treatment satisfaction and perceived effectiveness

  Approximately 1 week after intervention (post-intervention follow-up; variable depending on clinical trigger)

Study Arms (1)

Pain Registry Cohort

Participants enrolled in the Swiss Pain Registry. The cohort includes patients with acute and chronic pain receiving routine clinical care. No intervention is assigned; data are collected observationally through clinical documentation and patient-reported outcome measures over a follow-up period of up to 24 months.

Eligibility Criteria

• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of patients referred for interdisciplinary outpatient assessment and management of acute and chronic pain. The registry includes paediatric and adult patients of all genders across the full spectrum of acute and chronic pain conditions in routine clinical care.

You may qualify if:

• Signed informed consent by the participant or legal guardian for minors.
• Diagnosis of acute or chronic pain (chronic pain defined as pain lasting ≥ 3 months), including nociceptive, neuropathic, or mixed pain conditions.
• Referral for interdisciplinary outpatient pain assessment or treatment.
• Sufficient proficiency in German, French, Italian, or English to complete digital assessments (parental proxy allowed for paediatric participants if needed).
• All age groups included.

You may not qualify if:

• Lack of capacity to provide informed consent or absence of a legal guardian for minors.
• Inability to understand study languages and complete assessments even with assistance.
• Acute life-threatening conditions precluding participation.
• Site-specific safety considerations as determined by treating clinician.

Sponsors & Collaborators

• Insel Gruppe AG, University Hospital Bern: lead

Study Sites (1)

Universitätsklinik für Anästhesiologie und Schmerzmedizin, Inselspital, Universitätsspital Bern

Bern, Canton of Bern, 3010, Switzerland

Location

MeSH Terms

Conditions

Chronic Pain; Acute Pain

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Michael A Harnik, MD

  Universitätsklinik für Anästhesiologie und Schmerzmedizin, Inselspital, Universitätsspital Bern

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Michael A Harnik, MD

CONTACT

+41 31 632 30 27; michael.harnik@insel.ch

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Target Duration: 24 Months
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 1, 2026
• First Posted: July 21, 2026
• Study Start: July 15, 2026
• Primary Completion (Estimated): August 15, 2029
• Study Completion (Estimated): August 15, 2029
• Last Updated: July 21, 2026

Record last verified: 2026-07

Locations

CH (1)