NCT07716696

Brief Summary

Pericarditis is associated with symptoms such as chest pain, dyspnea, fatigue, cough, and anxiety, which can significantly impair functional capacity and quality of life. Pulmonary rehabilitation is a structured intervention designed to improve respiratory function and overall physical performance. This study aims to compare the effectiveness of pulmonary rehabilitation versus standard care in improving clinical symptoms and functional outcomes in patients with pericarditis.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
2mo left

Started Dec 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress76%
Dec 2025Oct 2026

Study Start

First participant enrolled

December 11, 2025

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

July 16, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 21, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 15, 2026

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 16, 2026

Last Updated

July 21, 2026

Status Verified

July 1, 2026

Enrollment Period

9 months

First QC Date

July 16, 2026

Last Update Submit

July 16, 2026

Conditions

Pericarditis

Keywords

Pulmonary RehabilitationPericarditisDyspneaChest PainFatigueCoughAnxiety

Outcome Measures

Primary Outcomes (1)

  • Dyspnea Severity

    Measured using Visual Analog Scale (VAS)

    Baseline and 8 weeks

Secondary Outcomes (4)

  • Pain Intensity

    Baseline and 8 weeks

  • Cough Severity

    Baseline and 8 weeks

  • Fatigue

    Time Frame: Baseline and 8 weeks

  • Anxiety

    Time Frame: Baseline and 8 weeks

Study Arms (2)

Pulmonary Rehabilitation Group

EXPERIMENTAL

Participants receive a structured pulmonary rehabilitation program including breathing exercises, aerobic training, and education sessions.

Other: Pulmonary Rehabilitation

Standard Care Group

ACTIVE COMPARATOR

Routine clinical management as prescribed by the treating physician without additional rehabilitation protocol.

Other: Standard Care

Interventions

Pulmonary RehabilitationOTHER

A structured program including breathing exercises, aerobic conditioning, and patient education administered over multiple weeks.

Pulmonary Rehabilitation Group
Standard CareOTHER

Routine clinical management as prescribed by the treating physician without additional rehabilitation protocol.

Standard Care Group

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosed with pericarditis Age between 18-65 years Both male and female participants Medically stable Able to participate in rehabilitation Willing to provide informed consent

You may not qualify if:

  • Severe cardiovascular or respiratory instability Other major pulmonary diseases Recent surgery or trauma Neurological disorders affecting participation Unwillingness to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

ULTH

Lahore, Punjab Province, Pakistan

Location

MeSH Terms

Conditions

PericarditisDyspneaChest PainFatigueCoughAnxiety Disorders

Interventions

Standard of Care

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesRespiration DisordersRespiratory Tract DiseasesSigns and Symptoms, RespiratorySigns and SymptomsPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsMental Disorders

Intervention Hierarchy (Ancestors)

Quality Indicators, Health CareQuality of Health CareHealth Services AdministrationHealth Care Quality, Access, and Evaluation

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Outcome assessors are blinded to group allocation to reduce bias.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Participants are randomly assigned to either pulmonary rehabilitation or standard care groups and followed over the intervention period.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor of Physical Therapy Student

Study Record Dates

First Submitted

July 16, 2026

First Posted

July 21, 2026

Study Start

December 11, 2025

Primary Completion (Estimated)

September 15, 2026

Study Completion (Estimated)

October 16, 2026

Last Updated

July 21, 2026

Record last verified: 2026-07

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be shared because this study was conducted as an academic research project. The informed consent obtained from participants did not include provisions for public data sharing, and the dataset contains sensitive personal health information. Data will be stored securely and used only for academic and research purposes in accordance with institutional ethics approval.

Locations

PA(1)