NCT07711886

Brief Summary

The reason for the recognised lack of epidemiological data of all NO conditions presenting to eye departments is attributed to the fact that they often fall in the grey zones between neuro-ophthalmologists, neurosurgeons and neurologists. . It is anticipated that the findings of the study may then help to support better service planning and resource allocation, as well as identifying any early recognition of rare or emerging patterns.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
840

participants targeted

Target at P75+ for all trials

Timeline
11mo left

Started Jan 2027

Shorter than P25 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 14, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

July 17, 2026

Completed
6 months until next milestone

Study Start

First participant enrolled

January 1, 2027

Expected
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2027

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2027

Last Updated

August 21, 2026

Status Verified

August 1, 2026

Enrollment Period

11 months

First QC Date

July 14, 2026

Last Update Submit

August 19, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Analysis of the incidence and patterns of presentation of common NO conditions compared to other published studies.

    From enrollment to 12 months

Secondary Outcomes (2)

  • Concordance rates between initial and final diagnosis.

    From enrollment to 12 months

  • Detailed analysis of rare presentations, with a view to share knowledge gained from this in educational meetings.

    From enrollment to 12 months

Interventions

no intervention required

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Consecutive patients seen at the Royal Wolverhampton NHS Trust's Eye Department who have a NO diagnosis and meet the eligibility criteria will be selected.

You may qualify if:

  • Participants aged ≥ 18 years.
  • Participants seen at the Royal Wolverhampton NHS Trust's Eye Department.
  • Participants with a diagnosis of NO.

You may not qualify if:

  • Participants aged \< 18 years.
  • Participants who do not have a diagnosis of NO.
  • Participants who have opted out of their data being used for research (National Data Opt-out).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 14, 2026

First Posted

July 17, 2026

Study Start (Estimated)

January 1, 2027

Primary Completion (Estimated)

December 1, 2027

Study Completion (Estimated)

December 1, 2027

Last Updated

August 21, 2026

Record last verified: 2026-08