NCT07711340

Brief Summary

Healthy individuals will be tested at different times of day to determine whether exercise at a non-expected time results in poorer performance.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
5mo left

Started Aug 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 14, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

July 17, 2026

Completed
15 days until next milestone

Study Start

First participant enrolled

August 1, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2026

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2026

Last Updated

July 17, 2026

Status Verified

July 1, 2026

Enrollment Period

2 months

First QC Date

July 14, 2026

Last Update Submit

July 14, 2026

Conditions

Healthy AdultExercise

Outcome Measures

Primary Outcomes (1)

  • Isometric quadriceps strength

    isometric quadriceps strength as determined during dynamometer testing

    15 minutes

Secondary Outcomes (2)

  • Isometric hamstring strength

    15 minutes

  • Isokinetic hamstring/quad strength

    15 minutes

Study Arms (3)

Regular Exercise

NO INTERVENTION

Exercise at the usual time

Early Exercise

EXPERIMENTAL

Exercise three hours earlier than usual

Behavioral: Time-driven dosing

Exercise Late

EXPERIMENTAL

Exercise three hours later than usual

Behavioral: Time-driven dosing

Interventions

Time-driven dosingBEHAVIORAL

Three hours earlier or later than usual exercise

Early ExerciseExercise Late

Eligibility Criteria

Age18 Years - 25 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy
  • years old
  • Lower body exercise three or more times per week, all at the same time of day (within 2 hour window)
  • Regular meal times (±1 hour window)
  • Regular sleep times (±1 hour window)

You may not qualify if:

  • Active or uncontrolled mental or physical health issues
  • Current musculoskeletal injury

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stanford University

Stanford, California, 94305, United States

Location

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Central Study Contacts

Jason Liu

CONTACT

650-493-5000 1-1-62410jason830@stanford.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

July 14, 2026

First Posted

July 17, 2026

Study Start

August 1, 2026

Primary Completion (Estimated)

September 30, 2026

Study Completion (Estimated)

December 31, 2026

Last Updated

July 17, 2026

Record last verified: 2026-07

Data Sharing

IPD Sharing
Will share

Deidentified outcome data from muscle testing will be shared on Dryad.

Access Criteria
open access

Locations

US(1)