Qigong Exercise for Muscles Strength and Quality of Life in Colorectal Cancer Patients Undergoing Chemotherapy

NCT07709429 | Not Yet Recruiting

• 1 other identifier: P.T.REC/012/005843
• Study Type: interventional
• Target: 38
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to evaluate therapeutic effect of Qigong for muscle strength and quality of life in colorectal cancer patients undergoing chemotherapy.

Conditions

Colorectal Cancer

Outcome Measures

Primary Outcomes (1)

• Muscle Strength

  Muscle strength of the upper and lower limbs will be assessed using the Lafayette Hand-Held Dynamometer. Muscle strength will be quantified as the maximum isometric force generated by the tested muscle groups, with higher values indicating greater muscle strength.

  12 weeks

Secondary Outcomes (1)

• Health-Related Quality of Life

  12 weeks

Study Arms (2)

Qigong Exercise + Conventional Exercise Program

EXPERIMENTAL

Participants will receive a supervised Baduanjin Qigong exercise program combined with conventional exercises, including pain-free range-of-motion exercises, low-intensity walking, and physical therapy education. The intervention will be conducted three times weekly for 12 weeks under physiotherapist supervision, while participants continue their prescribed chemotherapy and routine medical follow-up.

Other: Qigong Exercise; Other: Conventional Exercise Program

Conventional Exercise Program

ACTIVE COMPARATOR

Participants in this arm will receive a conventional exercise program consisting of pain-free range-of-motion exercises for the shoulder, elbow, wrist, hip, knee, and ankle joints, low-intensity walking, and physical therapy education to maintain daily activities. The intervention will be administered for 12 weeks, with three sessions per week. Participants will continue their prescribed chemotherapy and routine outpatient medical follow-up throughout the study and will not participate in any additional structured exercise program during the intervention period.

Other: Conventional Exercise Program

Interventions

Qigong Exercise OTHER

Participants will receive a supervised Baduanjin Qigong exercise program combined with conventional exercises, including pain-free range-of-motion exercises, low-intensity walking, and physical therapy education. The intervention will be conducted three times weekly for 12 weeks under physiotherapist supervision, while participants continue their prescribed chemotherapy and routine medical follow-up.

Qigong Exercise + Conventional Exercise Program

Conventional Exercise Program OTHER

Participants in this arm will receive a conventional exercise program consisting of pain-free range-of-motion exercises for the shoulder, elbow, wrist, hip, knee, and ankle joints, low-intensity walking, and physical therapy education to maintain daily activities. The intervention will be administered for 12 weeks, with three sessions per week. Participants will continue their prescribed chemotherapy and routine outpatient medical follow-up throughout the study and will not participate in any additional structured exercise program during the intervention period.

Conventional Exercise Program; Qigong Exercise + Conventional Exercise Program

Eligibility Criteria

• Age: 35 Years - 55 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age ranges between 35 and 55 years.
• Male \& female patients will participate in the study.
• All patients with colorectal cancer undergoing chemotherapy.
• All patients enrolled to the study will have their informed consent.
• The patients will be instructed to report any side effects during the management.

You may not qualify if:

• Presence Patients with psychological disturbance or mental illness.
• Cardiopulmonary disease.
• Hypotensive patients.
• Nerve, muscle, or joint disease, or other malignant tumors affecting movement.
• Autoimmune disease.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Physical Therapy, Cairo University

Giza, Egypt

Location

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Study Officials

• Amal Mohammed Abd El Baky, PhD

  Professor, Cairo University

  STUDY CHAIR

• Khadra Mohammed Ali, PhD

  Assist Professor, Cairo University

  STUDY DIRECTOR

• Eid Rizk El Gamal, PhD

  Assist. Professor, Al-Azhar University

  STUDY DIRECTOR

Central Study Contacts

Shrouk Mohamed Reda Abd Elaliem, M.Sc

CONTACT

+20 12 71384571; Shorouq.mohamed@nub.edu.eg

Khadra Mohammed Ali, PhD

CONTACT

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 12, 2026
• First Posted: July 16, 2026
• Study Start: July 20, 2026
• Primary Completion (Estimated): October 20, 2026
• Study Completion (Estimated): October 31, 2026
• Last Updated: July 16, 2026

Record last verified: 2026-07

Locations

EG (1)