Assessing Tissue Response to High-Velocity Thrust Manipulations on Capsule Length and Stiffness at the C5-C6 Facet Joint Capsule

NCT07704853 | Recruiting

• 1 other identifier: 2025-10
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This study is a quasi-experimental study collected quantitative data , with a pre-test-post-test design. Pre-intervention, baseline measurements of C5-C6 right facet joint length and width with the head of the treatment plinth downward at 45 and 90 degrees, (relative to the rest of the table) and stiffness at 90 degrees, were taken prior to applying the long-axis thrust manipulation. Post-intervention measures were taken immediately after a long axis thrust manipulation of C5-C6 and again at 24-hours after the manipulation. The baseline pre-intervention measures were then compared to the post-intervention measurements. The investigator performing the manipulation was blinded to the quantitative measurements of the ultrasound images. The ultrasound operator was blinded to the outcome of the manipulation.

Conditions

Neck Pain Musculoskeletal

Outcome Measures

Primary Outcomes (1)

• facet capsule length and width

  MSK US measure facet length and with in mm

  before intervention, immediately after, and at 24 hour follow up

Secondary Outcomes (2)

• Cervical motion

  before intervention, immediately after, and at 24 hour follow up

• elastography

  Before intervention, immediately after, and 24 hours after

Study Arms (1)

Sample

EXPERIMENTAL

C5-C6 long axis joint manipulation

Other: Long axis trust manipulation C5-C6

Interventions

Long axis trust manipulation C5-C6 OTHER

Long axis trust manipulation C5-C6

Sample

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy individuals between 18-35 without neck pain
• Able to to read and understand English

You may not qualify if:

• autoimmune disease
• down syndrome
• fusion, fracture
• spinal cord compression
• vascular pathology
• cancer,
• any other conditions that induce severe instability
• inflammation
• weakened bone.

Sponsors & Collaborators

• Florida Gulf Coast University: lead

Study Sites (1)

Florida Gulf Coast University Marieb Hall 101

Fort Myers, Florida, 33965, United States

RECRUITING

Central Study Contacts

Rob Sillevis, PhD

CONTACT

239-7454312; rsillevis@fgcu.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 10, 2026
• First Posted: July 15, 2026
• Study Start: February 4, 2025
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): October 1, 2026
• Last Updated: July 23, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)