Postoperative Analgesic Efficacy of ACB+iPACK vs FTB+Selective Tibial+Obturator Blocks in ACL Reconstruction
ACL-Analgesia
Evaluation of Postoperative Analgesic Efficacy in Anterior Cruciate Ligament Reconstruction: Ultrasound-Guided Adductor Canal Block Combined With iPACK Block Versus Femoral Triangle Block Combined With Selective Tibial and Obturator Nerve Blocks at Da Nang Hospital
1 other identifier
interventional
100
0 countries
N/A
Brief Summary
This prospective, comparative study aims to evaluate the postoperative analgesic efficacy of ultrasound-guided Adductor Canal Block (ACB) combined with iPACK block versus Femoral Triangle Block (FTB) combined with selective tibial nerve block and obturator nerve block in patients undergoing arthroscopic anterior cruciate ligament (ACL) reconstruction. The primary objective is to determine which regional anesthesia regimen provides superior pain relief at rest and during movement. The secondary objectives include assessing morphine consumption, motor blockade using the Bromage score, patient satisfaction, and potential adverse effects of these anesthesia techniques.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jul 2026
Shorter than P25 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2026
CompletedFirst Submitted
Initial submission to the registry
July 8, 2026
CompletedFirst Posted
Study publicly available on registry
July 14, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
March 1, 2027
July 14, 2026
July 1, 2026
8 months
July 8, 2026
July 8, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Visual Analog Scale (VAS) for Pain at Rest and Movement
Evaluating pain scores using the Visual Analog Scale (VAS) at rest and during knee flexion at 0, 1, 3, 6, 9, 12, 18, and 24 hours postoperatively
Within the first 24 hours postoperatively
Secondary Outcomes (3)
Total Rescue Morphine Consumption
Within the first 24 hours postoperatively
Motor Blockade Assessment using Bromage Score
Within the first 24 hours postoperatively
Patient Satisfaction Score
24 hours postoperatively
Study Arms (2)
ACB and iPACK Block Group
EXPERIMENTALUltrasound-guided Adductor Canal Block (10ml levobupivacaine 0.2%) and iPACK block (15ml levobupivacaine 0.2%) combined with standard multimodal analgesia (Paracetamol + Diclofenac).
FTB, Tibial and Obturator Blocks Group
ACTIVE COMPARATORUltrasound-guided Femoral Triangle Block (10ml levobupivacaine 0.2%), selective Tibial Nerve Block (5ml levobupivacaine 0.2%), and Obturator Nerve Block (10ml levobupivacaine 0.2%) combined with standard multimodal analgesia
Interventions
Ultrasound-guided administration of 10 mL levobupivacaine 0.2% into the adductor canal space to provide postoperative analgesia
Ultrasound-guided administration of 15 mL levobupivacaine 0.2% into the space between the popliteal artery and the posterior capsule of the knee to provide posterior knee analgesia.
Ultrasound-guided administration of 10 mL levobupivacaine 0.2% at the distal apex of the femoral triangle to provide anterior and medial knee analgesia
Ultrasound-guided administration of 5 mL levobupivacaine 0.2% around the tibial nerve in the popliteal fossa
Ultrasound-guided administration of 10 mL levobupivacaine 0.2% targeting the anterior and posterior branches of the obturator nerve within the fascial planes between the adductor muscles.
Eligibility Criteria
You may qualify if:
- Age 16 years and older
- Patients undergoing elective arthroscopic anterior cruciate ligament (ACL) reconstruction
- ASA physical status I-II
- Indicated for spinal anesthesia
- Provided informed consent
You may not qualify if:
- Infection at the injection site
- Spinal cord or lower limb nerve injury
- Contraindications to regional anesthesia (Levobupivacaine)
- Known allergy to Paracetamol or Diclofenac
- Coagulopathy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Da Nang Hospitallead
Related Publications (3)
Bai S, Hu A, Li W, Chen Y, Li X, Song X, Liu D, Ba Y, Chen Q, Liu X, Li Y, Zhang H, Xie Y, Wang X. Comparing the analgesic effects of femoral triangle block and adductor canal block following total knee arthroplasty: a systematic review and meta-analysis. BMC Anesthesiol. 2025 Apr 23;25(1):202. doi: 10.1186/s12871-025-03073-3.
PMID: 40269716RESULTJaeger P, Nielsen ZJ, Henningsen MH, Hilsted KL, Mathiesen O, Dahl JB. Adductor canal block versus femoral nerve block and quadriceps strength: a randomized, double-blind, placebo-controlled, crossover study in healthy volunteers. Anesthesiology. 2013 Feb;118(2):409-15. doi: 10.1097/ALN.0b013e318279fa0b.
PMID: 23241723RESULTGhodki PS, Shalu PS, Sardesai SP. Ultrasound-guided adductor canal block versus femoral nerve block for arthroscopic anterior cruciate ligament repair under general anesthesia. J Anaesthesiol Clin Pharmacol. 2018 Apr-Jun;34(2):242-246. doi: 10.4103/joacp.JOACP_172_17.
PMID: 30104837RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Nhan T Phan, MD. MSc
Da Nang Hospital
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 8, 2026
First Posted
July 14, 2026
Study Start
July 1, 2026
Primary Completion (Estimated)
March 1, 2027
Study Completion (Estimated)
March 1, 2027
Last Updated
July 14, 2026
Record last verified: 2026-07