Ultrasound Guidance vs. Landmark Technique for Catheter Malposition in IJV Catheterization

NCT07701720 | Not Yet Recruiting

• 1 other identifier: 321/2026
• Study Type: observational
• Target: 204
• Locations: 0 countries
• Sites: N/A

Brief Summary

Central venous catheterization (CVC) via the internal jugular vein (IJV) is a fundamental procedure in anesthesia and intensive care for hemodynamic monitoring, fluid resuscitation, and vasoactive drug administration. While modern clinical guidelines strongly advocate for ultrasound (USG) guidance, the traditional anatomical landmark technique remains widely utilized due to equipment availability or clinician habits. Proper positioning of the catheter tip is critical to prevent severe long-term complications; however, comparative data regarding catheter tip malposition between these two routine techniques-especially when confirmed by postprocedural bedside chest X-ray-require further prospective evaluation. Objective: The primary objective of this prospective observational study is to compare ultrasound-guided versus landmark techniques for internal jugular vein catheterization with respect to catheter tip malposition, as determined by postprocedural bedside chest X-ray. Secondary objectives include the evaluation of the number of needle redirections, first-attempt success rate, total procedure time, and the incidence of mechanical complications (such as accidental arterial puncture or hematoma formation)

Conditions

Catheter Malposition; Central Venous Catheterization

Outcome Measures

Primary Outcomes (1)

• Incidence of catheter tip malposition

  Assessed on postoperative bedside chest X-ray, immediately following the procedure

Secondary Outcomes (1)

• Incidence of Procedural Mechanical Complications

  During the procedure and up to 24 hours post-operatively.

Study Arms (2)

Ultrasound-guided group

IJV catheterization performed under real-time ultrasound guidance

Procedure: Ultrasound-Guided Technique

Landmark technique group

IJV catheterization performed via anatomical landmark technique

Procedure: Landmark Technique

Interventions

Ultrasound-Guided Technique PROCEDURE

Internal jugular vein catheterization performed with real-time ultrasound visualization of the vein to guide needle insertion.

Ultrasound-guided group

Landmark Technique PROCEDURE

Internal jugular vein catheterization performed using external anatomical landmarks without real-time ultrasound guidance.

Landmark technique group

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult and elderly patients (18-75 years) undergoing elective or scheduled surgery in the general operating room unit of Dicle University Faculty of Medicine Hospital who require central venous catheterization via the internal jugular vein as part of routine perioperative care. The catheterization technique (ultrasound-guided or landmark) reflects the routine practice of the performing physician; no technique is assigned by the study for research purposes.

You may qualify if:

• Patients aged 18-75 undergoing surgery requiring central venous (internal jugular) catheterization

You may not qualify if:

• Refusal to participate
• age \<18 or \>75
• emergency surgery
• coagulopathy
• infection, prior surgery, or prior cannulation at the insertion site
• allergy to ultrasound gel

Sponsors & Collaborators

• Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital: lead

Related Publications (1)

• Riaz A, Shan Khan RA, Salim F. Ultrasound guided internal jugular venous cannulation: comparison with land-mark technique. J Coll Physicians Surg Pak. 2015 May;25(5):315-9.

  PMID: 26008653 BACKGROUND

Central Study Contacts

Fikret Salık Assoc. Prof. Dr.

CONTACT

0507 621 41 25; fikretsalik@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Target Duration: 2 Days
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Medicine Doctor Associate Professor in Anesthesiology

Study Record Dates

• First Submitted: July 8, 2026
• First Posted: July 14, 2026
• Study Start: July 15, 2026
• Primary Completion (Estimated): October 15, 2026
• Study Completion (Estimated): October 15, 2026
• Last Updated: July 14, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share