Evaluation of Wear Resistance of CAD/CAM Hybrid Ceramic and Nano-Hybrid Composite Overlays in Endodontically Treated Molars and Their Effect on Natural Antagonist Teeth
1 other identifier
interventional
24
0 countries
N/A
Brief Summary
This randomized clinical trial aims to to evaluate and compare the 24-month surface wear of the restoration and the surface wear of the opposing natural tooth structure of CAD/CAM Hybrid Ceramic (SHOFU Hard blocks) versus Resin-based Composite (BRILLIANT Crios) overlays, utilizing a digital subtraction methodology (Intraoral Scanner and Geometrical Subtraction Software) in endodontically treated molar teeth.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jul 2026
Typical duration for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 30, 2026
CompletedStudy Start
First participant enrolled
July 1, 2026
CompletedFirst Posted
Study publicly available on registry
July 7, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2028
ExpectedStudy Completion
Last participant's last visit for all outcomes
July 1, 2028
July 7, 2026
June 1, 2026
2 years
June 30, 2026
June 30, 2026
Conditions
Outcome Measures
Primary Outcomes (1)
Annual wear rate
Digital Scanner +Geometrical Subtraction Software
24 months
Secondary Outcomes (1)
Functional properties, Biological properties and Esthetic properties
24 months
Study Arms (2)
SHOFU Hard blocks
EXPERIMENTALCAD/CAM Hybrid Ceramic, Overlay restored using the SHOFU cementation system.
BRILLIANT Crios
ACTIVE COMPARATORResin-based Composite, Overlay restored using the Coltène cementation system.
Interventions
CAD/CAM Hybrid Ceramic, Overlay restored using the SHOFU cementation system.
Resin-based Composite, Overlay restored using the Coltène cementation system.
Eligibility Criteria
You may qualify if:
- Age between 22 and 45 years.
- Low to moderate caries risk.
- Normal occlusion.
- Absence of signs or symptoms of temporomandibular joint (TMJ) disorders.
- Satisfactory oral hygiene.
- Medically fit to receive routine restorative dental treatment.
- Permanent molars.
- Asymptomatic endodontically treated teeth.
- Homogeneous root canal fillings extending 1-2 mm from the radiographic apex.
- Compound cavities.
- Favorable occlusion.
- Presence of both an adjacent tooth and a sound opposing tooth in occlusion
You may not qualify if:
- \* Presence of bruxism.
- Poor patient cooperation.
- Inability or unwillingness to attend follow-up appointments.
- Anticipated travel during the study period.
- Poor oral hygiene.
- Chronic or advanced periodontitis.
- Known allergies to any of the materials used in the study.
- Patients who are pregnant or breastfeeding.
- Teeth with \<1" mm" of residual wall thickness.
- Deep subgingival cavity margins.
- Severe periodontal problems.
- Radiographic signs of apical pathology.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- PhD Candidate
Study Record Dates
First Submitted
June 30, 2026
First Posted
July 7, 2026
Study Start
July 1, 2026
Primary Completion (Estimated)
July 1, 2028
Study Completion (Estimated)
July 1, 2028
Last Updated
July 7, 2026
Record last verified: 2026-06