NCT07687303

Brief Summary

The study aims to: Explore the relationship between MV modes on the IA, MP and GT tolerance among mechanically ventilated patients.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P50-P75 for all trials

Timeline
3mo left

Started Aug 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress1%
Aug 2026Nov 2026

First Submitted

Initial submission to the registry

June 23, 2026

Completed
14 days until next milestone

First Posted

Study publicly available on registry

July 7, 2026

Completed
25 days until next milestone

Study Start

First participant enrolled

August 1, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2026

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2026

Last Updated

July 7, 2026

Status Verified

July 1, 2026

Enrollment Period

2 months

First QC Date

June 23, 2026

Last Update Submit

July 4, 2026

Conditions

Keywords

mechanical ventilator modesintraabdominal pressure

Outcome Measures

Primary Outcomes (3)

  • intra-abdominal pressure "IAP"

    IAP will be measured through foly catheter

    day 1

  • mechanical power

    it will be: MP (J/ min) =0.098×RR×Vt × \[Peak Pressure-(DP/2)\] measured through folly catheter

    day 1

  • gastric tube tolerance

    The GT tolerance will be presented as yes if the patient was on GT feeding, and no, if the patient had delayed gastric emptying and converted to gastric drain

    day 1

Study Arms (3)

SIMV group

this group are attached with MV on SIMV mode

CPAP group

this group are attached with MV on CPAP mode

BiPAP group

this group are attached with MV on BiPAP mode

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

A convenient sample

You may qualify if:

  • adult patients requiring MV in ICU

You may not qualify if:

  • patients with abdominal or chest trauma,
  • patients with intra abdominal pathologies,
  • patients who had received more than 10 units of red blood cells or more than 5 liters of intravenous liquids over the last 24 h,
  • patients with sepsis or hepatic, or renal dysfunction,
  • patients in positions other than supine, and
  • body mass index (BMI) ≥ 30 kg/m2.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Nursing, Damanhour University

Damanhūr, Egypt

RECRUITING

Related Publications (1)

  • https://r.search.yahoo.com/_ylt=AwrFYna.5DpqRgIAKKRXNyoA;_ylu=Y29sbwNiZjEEcG9zAzEEdnRpZAMEc2VjA3Ny/RV=2/RE=1783454142/RO=10/RU=https%3a%2f%2fpmc.ncbi.nlm.nih.gov%2farticles%2fPMC3733186%2f/RK=2/RS=5S3GXdIx14M.h5tX6E6bTclSBZw-

    BACKGROUND

Related Links

Study Officials

  • sahar youness youness, professor

    professor of emergency and critical nursing

    PRINCIPAL INVESTIGATOR

Central Study Contacts

heba attia lecturer, lecturer

CONTACT

Alaa Mustafa assistant professor, assistant professor

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Target Duration
3 Days
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Faculty member " lecturer"

Study Record Dates

First Submitted

June 23, 2026

First Posted

July 7, 2026

Study Start

August 1, 2026

Primary Completion (Estimated)

October 1, 2026

Study Completion (Estimated)

November 1, 2026

Last Updated

July 7, 2026

Record last verified: 2026-07

Data Sharing

IPD Sharing
Will share

ASD123456789

Shared Documents
STUDY PROTOCOL
Time Frame
Octuber, 2026 and will be available for 5 years
Access Criteria
any researcher will be able to access
More information

Locations