Postoperative Pulmonary Complications in Adult PNL Patients

NCT06462976 | Completed

• 1 other identifier: 2024/99
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to investigate the effect of different surgical positions (supine/prone) on lung mechanical power (MP) and its relationship with postoperative pulmonary complications in patients planned to percutaneous nephrolithotomy (PNL) under general anesthesia.

Conditions

Postoperative Pulmonary Complication; Mechanical Power

Outcome Measures

Primary Outcomes (1)

• mechanical power

  mechanical power=0.098\*minute ventilation \*(Ppeak-0.5\*(Pplato-PEEP)

  2 year

Study Arms (2)

supine

Which group the patients will be included in will be determined by the surgical team based on the location and number of stones. The patient's values will be recorded in that position.

Other: mechanical power calculation

prone

Which group the patients will be included in will be determined by the surgical team based on the location and number of stones. The patient's values will be recorded in that position.

Other: mechanical power calculation

Interventions

mechanical power calculation OTHER

Mechanical Power= 0.098×Minute ventilation× (peak pressure - 0.5 (plato pressure-PEEP)). These parameters are monitored on the monitor while the patient is mechanically ventilated and placed into the equation

prone; supine

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who are aged 18-75 agree to participate in the study

You may qualify if:

• Patients who will undergo elective percutaneous nephrolithotomy and agree to participate in the study.
• ASA 1-3 patient

You may not qualify if:

• Patients with acute and chronic hypoxemia (PaO2\<65mmHg, SpO2\<95 in room air)
• Patients with BMI\>35
• Patients with obstructive sleep apnea syndrome
• Patients with ASA 4 and above
• Pregnant patients
• Pneumonia, COPD attack etc. before the operation. people with lung disease
• Unstable patients such as uncontrolled hypertension, decompensated heart
• Mentally retarded and uncooperative patients

Sponsors & Collaborators

• TC Erciyes University: lead

Study Sites (1)

Gamze Talih

Kayseri, Kayseri, Turkey (Türkiye)

Location

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 4, 2024
• First Posted: June 17, 2024
• Study Start: July 1, 2025
• Primary Completion: January 31, 2026
• Study Completion: April 15, 2026
• Last Updated: May 6, 2026

Record last verified: 2025-06

Locations

TU (1)