Relationship Between Clinical Status and Nerve Conduction Test Findings in Patients With Unilateral Hemiplegia

NCT07685691 | Completed

• 1 other identifier: BASKENT UNIVERSITY KA24/315
• Study Type: observational
• Target: 72
• Locations: 1 country
• Sites: 1

Brief Summary

Stroke-related hemiplegia may be accompanied by peripheral nerve conduction abnormalities, which may contribute to motor impairment and functional limitations. However, the frequency of these abnormalities and their relationship with clinical status have not been fully characterized. This single-center observational study aims to evaluate the frequency of peripheral nerve conduction abnormalities identified by nerve conduction studies in patients with unilateral hemiplegia and to examine their association with motor and functional clinical assessment scores. The findings may contribute to a better understanding of peripheral nerve involvement in stroke rehabilitation.

Conditions

Stroke; Hemiplegia; Intracranial Hemorrhage, Spontaneous

Keywords

nerve conduction study; Electrophysiology; Fugl-Meyer Assessment; Rehabilitation

Outcome Measures

Primary Outcomes (1)

• Association Between Peripheral Nerve Conduction Abnormalities and Clinical Assessment Scores

  To evaluate the association between peripheral nerve conduction abnormalities identified by standardized nerve conduction studies and motor and functional outcome measures in patients with unilateral hemiplegia secondary to ischemic or hemorrhagic stroke. Peripheral nerve conduction abnormalities identified by standardized nerve conduction studies will also be described.

  Baseline

Secondary Outcomes (4)

• Fugl-Meyer Assessment (FMA) Score (Upper and Lower Extremities)

  Baseline

• Functional Independence Measure (FIM) Score

  Baseline

• Timed Up and Go Test (TUG)

  Baseline

• Tetrax Fall Index

  At study enrollment (baseline)

Study Arms (1)

Patients With Unilateral Post-Stroke Hemiplegia

Patients with unilateral post-stroke hemiplegia who underwent standardized nerve conduction studies and clinical assessments, including motor and functional outcome measures.

Diagnostic Test: Nerve Conduction Study

Interventions

Nerve Conduction Study DIAGNOSTIC_TEST

Standardized motor and sensory nerve conduction studies were performed to evaluate peripheral nerve conduction abnormalities in patients with unilateral post-stroke hemiplegia. The test was used as a diagnostic assessment and was not part of a therapeutic intervention.

Also known as: NCS

Patients With Unilateral Post-Stroke Hemiplegia

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adults with unilateral hemiplegia secondary to ischemic or hemorrhagic stroke who were recruited from the Department of Physical Medicine and Rehabilitation at a single tertiary care center. All participants underwent standardized nerve conduction studies and clinical assessments according to the study protocol.

You may qualify if:

• Adults (≥18 years of age).
• Unilateral hemiplegia secondary to ischemic or hemorrhagic stroke, or intracranial hemorrhage.
• Ability to undergo standardized nerve conduction studies and clinical assessments.
• Provision of written informed consent.

You may not qualify if:

• Bilateral hemiplegia.
• Hemiplegia secondary to benign or malignant intracranial tumors.
• Upper or lower extremity fracture, amputation, skin lesions preventing electrophysiological testing, or diagnosed peripheral vascular disease.
• Concomitant neurological disorders that may affect motor function or peripheral nerve conduction (e.g., Parkinson's disease, multiple sclerosis, encephalitis).
• Contraindications to nerve conduction studies (e.g., cardiac pacemaker or inability to safely undergo the examination).
• Inability to cooperate with or tolerate nerve conduction studies.

Sponsors & Collaborators

• Baskent University: lead

Study Sites (1)

Başkent University Adana Dr. Turgut Noyan Application and Research Center

Adana, 01250, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Stroke; Hemiplegia; Intracranial Hemorrhages

Interventions

Nerve Conduction Studies

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Paralysis; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Hemorrhage; Pathologic Processes

Intervention Hierarchy (Ancestors)

Diagnostic Techniques, Neurological; Diagnostic Techniques and Procedures; Diagnosis; Electrodiagnosis

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 30 Days
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 29, 2026
• First Posted: July 6, 2026
• Study Start: October 4, 2024
• Primary Completion: May 20, 2026
• Study Completion: June 24, 2026
• Last Updated: July 29, 2026

Record last verified: 2026-07

Locations

TU (1)