Comparison of Laser Hemorrhoidoplasty Versus Conventional Milligan Morgan Hemorrhoidectomy in Grade II and III Hemorrhoids

NCT07678814 | Completed

• 1 other identifier: ERB166 / 9 / 11-06-2024/S1 ERB
• Study Type: interventional
• Target: 96
• Locations: 1 country
• Sites: 1

Brief Summary

Hemorrhoidal disease is one of the most common anorectal disorders. Conventional Milligan Morgan Hemorrhoidectomy remains the standard treatment but is associated with considerable postoperative pain. Laser Hemorrhoidoplasty has emerged as a minimally invasive alternative. This randomized controlled trial compares postoperative pain, patient satisfaction, and hospital stay between Laser Hemorrhoidoplasty and conventional hemorrhoidectomy in patients with Grade II and Grade III hemorrhoids.

Conditions

Hemorrhoids Second Degree; Hemorrhoids Third Degree; Internal Hemorrhoids

Keywords

Laser Hemorrhoidoplasty; Milligan Morgan Hemorrhoidectomy; Randomized Controlled Trial; Postoperative Pain; Patient Satisfaction

Outcome Measures

Primary Outcomes (2)

• Postoperative Pain

  Pain measured using Visual Analogue Scale (VAS).

  Post Operative period: (6) Six Hourly in first 48 Hours, at 1 week post operative period & at 1 month post operatively.

• Patient Satisfaction

  Patient satisfaction assessed using Likert-scale questionnaire.

  1 month postoperative

Study Arms (2)

Laser Hemorrhoidoplasty

EXPERIMENTAL

Patients underwent Laser Hemorrhoidoplasty using diode laser energy applied to hemorrhoidal tissue.

Procedure: Laser Hemorrhoidoplasty

Milligan Morgan Hemorrhoidectomy

ACTIVE COMPARATOR

Patients underwent conventional open Milligan Morgan Hemorrhoidectomy.

Procedure: Milligan Morgan Hemorrhoidectomy

Interventions

Laser Hemorrhoidoplasty PROCEDURE

Patients randomized to the intervention group underwent Laser Hemorrhoidoplasty under spinal anesthesia. A diode laser probe was introduced into the hemorrhoidal tissue through a small mucosal entry point under direct visualization using an anoscope. Controlled laser energy was delivered submucosally to achieve coagulation, shrinkage, and fixation of the hemorrhoidal cushions while preserving the surrounding anoderm and mucosa. The procedure was performed according to standard surgical protocols with the aim of reducing postoperative pain, bleeding, and recovery time.

Laser Hemorrhoidoplasty

Milligan Morgan Hemorrhoidectomy PROCEDURE

Patients randomized to the control group underwent conventional open Milligan Morgan Hemorrhoidectomy under spinal anesthesia. The hemorrhoidal pedicles were identified, ligated, and excised using standard surgical techniques. The wounds were left open with preservation of mucocutaneous bridges between excision sites. Hemostasis was achieved as required. Patients received routine postoperative care and follow-up according to institutional protocols.

Milligan Morgan Hemorrhoidectomy

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥18 years Grade II hemorrhoids Grade III hemorrhoids Both genders

You may not qualify if:

• Rectal prolapse Anal fissure Anorectal malignancy Pregnancy or lactating mothers

Sponsors & Collaborators

• Allama Iqbal Medical College: lead

Study Sites (1)

Jinnah Hospital, Lahore.

Lahore, Punjab Province, Pakistan

Location

MeSH Terms

Conditions

Pain, Postoperative; Patient Satisfaction

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms; Treatment Adherence and Compliance; Health Behavior; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr. Muhammad, FCPS General Surgery Resident

Study Record Dates

• First Submitted: June 25, 2026
• First Posted: July 1, 2026
• Study Start: September 1, 2025
• Primary Completion: February 28, 2026
• Study Completion: March 31, 2026
• Last Updated: July 1, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)