NCT07677540

Brief Summary

Post-thoracotomy pain syndrome (PTPS) is a prevalent complication that significantly impacts patients' quality of life, with reported incidence ranging from 25% to 90%. This study evaluated the effectiveness of continuous erector spinae plane (ESP) block compared to thoracic epidural analgesia (TEA), the current gold standard, in preventing PTPS. Our goal was to compare the incidence of PTPS between patients who received ESP block and those who underwent TEA. Additional goals included assessing postoperative pain levels, analgesic consumption, and complications related to the anesthesia techniques.

Trial Health

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Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
34

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Sep 2023

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 12, 2023

Completed
2.8 years until next milestone

First Submitted

Initial submission to the registry

June 18, 2026

Completed
12 days until next milestone

First Posted

Study publicly available on registry

June 30, 2026

Completed
1 day until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2026

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2026

Completed
Last Updated

June 30, 2026

Status Verified

June 1, 2026

Enrollment Period

2.8 years

First QC Date

June 18, 2026

Last Update Submit

June 24, 2026

Conditions

Thoracic Surgery

Outcome Measures

Primary Outcomes (1)

  • Incidence of post thoracotomy pain syndrome

    Incidence of post thoracotomy pain syndrome 3 months post operatively

    3 months post operatively

Study Arms (2)

ESP block

Patients who recieved ESP block for thoracic surgery

Procedure: ESP block

Thoracic epidural

Patients who recieved thoracic epidural for thoracic surgery

Procedure: Thoracic epidural

Interventions

ESP blockPROCEDURE

Performance of ESP block for pain relief after thoracic surgery

ESP block
Thoracic epiduralPROCEDURE

Performance of thoracic epidural for pain relief after thoracic surgery

Thoracic epidural

Eligibility Criteria

Age18 Years - 99 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Eligible subjects are adult patients who presented for elective thoracic surgery under general anesthesia and underwent TEA or ESP.

You may qualify if:

  • \. Ages 18-65 years 2. Presenting for elective thoracic surgery under general anesthesia. 3. Undergoing either ESP or TEA prior to surgery.

You may not qualify if:

  • \. Any CNS and/or psychiatric disease. 2. Patients who are unable to complete the pain survey for any reason. 3. Patients who had baseline chronic pain around the surgical incision.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Meir Medical Center

Kfar Saba, Israel

RECRUITING

MeSH Terms

Interventions

Tea

Intervention Hierarchy (Ancestors)

Plant PreparationsBiological ProductsComplex MixturesBeveragesDiet, Food, and NutritionPhysiological PhenomenaFood and Beverages

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr

Study Record Dates

First Submitted

June 18, 2026

First Posted

June 30, 2026

Study Start

September 12, 2023

Primary Completion

July 1, 2026

Study Completion

July 31, 2026

Last Updated

June 30, 2026

Record last verified: 2026-06

Locations

IL(1)