NCT07676630

Brief Summary

24 volunteer professional female volleyball players (aged 16-21), licensed in the Turkish Volleyball Federation (TVF) Women's Volleyball League 2 and 3, will be included in the study. Participants will be randomized into intervention (n=12) and control (n=12) groups using www.randomizer.org. The intervention group will receive an 8-week (3 days/week) neuro-athletic exercise training program, including eye warm-up exercises and volleyball-specific visual and motor coordination stations, in addition to their regular training. The control group will continue with regular training only. Both groups will have equal total training time. Visual attention and decision-making strategies will be measured with a wearable eye-tracking system (Pupil Labs Invisible) during a serve task. Cortical activation (oxygenated and deoxygenated hemoglobin levels) in the frontal cortex during the same serve task will be measured simultaneously with functional near-infrared spectroscopy (fNIRS). Sport-specific physical fitness will be evaluated with the T-Agility Test, radar gun serve speed measurement, VERT wearable jump analysis system, Y-Balance Test, and sit-and-reach test. All assessments will be conducted before training begins and after the 8-week program. The study aims to determine whether neuro-athletic exercise training improves cortical activation, visual attention, decision-making processes, and sport-specific physical fitness parameters in professional female volleyball players, compared to a control group receiving regular training only.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
2mo left

Started Feb 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress73%
Feb 2026Sep 2026

Study Start

First participant enrolled

February 20, 2026

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

June 24, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 30, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2026

Expected
29 days until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2026

Last Updated

June 30, 2026

Status Verified

June 1, 2026

Enrollment Period

6 months

First QC Date

June 24, 2026

Last Update Submit

June 24, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Functional near-infrared spectroscopy

    Cortical Activation During Serve Task (fNIRS), measured using functional near-infrared spectroscopy (fNIRS) during a serve task, comparing pre-task, during-task, and post-task signal changes. Change in oxygenated (HbO) and deoxygenated (HbR) hemoglobin levels in the frontal cortex.

    Baseline and after 8 weeks

  • Pupil Lab Invisible Eye Tracker

    Visual Attention and Decision-Making (Eye-Tracking Parameters). Measured using a wearable eye-tracking system (Pupil Labs Invisible) during a serve task, including total fixation duration and visual scan path parameters, automatically quantified using Pupil Player software. Measured change in gaze fixation duration and visual search patterns

    Baseline and after 8 weeks

Secondary Outcomes (5)

  • T-Agility Test

    Baseline and after 8 weeks

  • Serve Speed

    Baseline and after 8 weeks

  • Vertical Jump Performance

    Baseline and after 8 weeks

  • Y-Balance Test

    Baseline and after 8 weeks

  • Sit-and-Reach Test

    Baseline and after 8 weeks

Study Arms (2)

Intervention Group

EXPERIMENTAL

Participants will receive an 8-week (3 days/week) neuroscience-based exercise training program in addition to their regular volleyball training. The program includes eye warm-up exercises (eye massage, palming) and volleyball-specific visual and motor coordination stations (Saccade, Anti-Saccade, Smart Optometry, Brock String, Star Chart, and Pinhole Glasses Small Area Game stations).

Behavioral: Exercise

Control Group

NO INTERVENTION

Participants will continue with their regular volleyball training routine, including standard warm-up and cool-down, without any additional neuroscience-based exercise intervention. Total training time will be kept equal to the intervention group.

Interventions

ExerciseBEHAVIORAL

An 8-week (3 days/week) structured program added to regular training, combining: (1) eye warm-up exercises (eye massage, palming) and (2) volleyball-specific visual-motor coordination stations, including Saccade, Anti-Saccade, and Smart Optometry stations (targeting visual tracking, reaction speed, and eye-hand coordination), Brock String (depth perception and eye-hand coordination), Star Chart station (visual scanning and spatial awareness), and Pinhole Glasses Small Area Game (restricted peripheral vision to enhance focused attention and quick decision-making). Sessions are conducted by a physiotherapist, with total training time matched to the control group.

Intervention Group

Eligibility Criteria

Age16 Years - 21 Years
Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Licensed female volleyball player in the Turkish Volleyball Federation (TVF) Women's Volleyball League 2 or League 3
  • Aged between 16 and 21 years
  • Actively participating in the sport for at least 3 years

You may not qualify if:

  • Any history of musculoskeletal surgery
  • An injury within the last 3 months that prevented participation in training or competition
  • Any diagnosed visual impairment, visual function disorder, or vestibular system-related problem

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Istinye University Physiotherapy and Rehabilitation Practice and Research Center

Istanbul, Zeytinburnu, 34010, Turkey (Türkiye)

RECRUITING

Related Publications (1)

  • Soylu, C.; Altundag, E. Rewiring for Victory: Neuro-Athletic Training Enhances Flexibility, Serve Speed, and Upper Limb Performance in Elite Volleyball Players-A Randomized Controlled Trial. Appl. Sci. 2024, 14, 11102. https://doi.org/10.3390/app142311102

    RESULT

MeSH Terms

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • OZGE ECEM SENEL, PT, MSc

    Istinye University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

OZGE ECEM SENEL, PT, MSc

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Research Assisstant, PT, MSc

Study Record Dates

First Submitted

June 24, 2026

First Posted

June 30, 2026

Study Start

February 20, 2026

Primary Completion (Estimated)

September 1, 2026

Study Completion (Estimated)

September 30, 2026

Last Updated

June 30, 2026

Record last verified: 2026-06

Locations