Functional Progressive Resistive Training and Cerebral Palsy

NCT07675343 | Not Yet Recruiting

• 1 other identifier: P.T.REC/012/006023
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

Functional Progressive Resistive Exercise (FPRE) is a strengthening approach that combines functional movement activities with progressively increased resistance. It involves performing task-oriented exercises, such as sit-to-stand, stair climbing, and walking-related activities, while gradually increasing the load to enhance muscle strength, endurance, and functional performance. FPRE is widely used in rehabilitation programs to improve mobility and the ability to perform activities of daily living in various populations, including children with neurological and musculoskeletal disorders.

Conditions

Cerebral Palsy

Keywords

cerebral palsy; functional progressive resistive exercise; bone mineral density; balance

Outcome Measures

Primary Outcomes (2)

• Dual-energy X-ray absorptiometry (DXA)

  The most common test for bone mineral density is a Dual-energy X-ray absorptiometry (DXA) scan. It is: Painless and non-invasive Quick (usually 10-20 minutes) Low radiation exposure Most often performed on the hip and lower spine. Bone mineral density (BMD) is a measure of the amount of mineral (mainly calcium and phosphorus) present in a specific volume of bone. It reflects bone strength and is used to assess the risk of fractures and diagnose osteoporosis.

  3month

• biodex balance system

  The Biodex Balance System is a computerized device used to assess and improve static and dynamic balance, postural stability, and neuromuscular control. It consists of a movable platform that can be adjusted to different levels of stability, allowing clinicians and researchers to evaluate an individual's ability to maintain balance under varying conditions.

  3 month

Study Arms (2)

functional progressive resistive exercise and designed physical therapy program

EXPERIMENTAL

Other: functional progressive resistive exercise and designed physical therapy program

designed physical therapy program

EXPERIMENTAL

Other: designed physical therapy program

Interventions

designed physical therapy program OTHER

conventional physical therapy program including reinforcement of the normal motor development, reflex inhibiting patterns, postural reaction, stretching, strengthening exercises, and gait training was applied to children in the control group

designed physical therapy program

functional progressive resistive exercise and designed physical therapy program OTHER

specially designed physical therapy program in addition to functional progressive resistive exercises for 60 min (30 min designed P.T program and other 30 min for brain gym exercises), 3 sessions/ week for 3 successive months. 6 functional progressive resistive exercises will be selected: 1. Sit-to-Stand Exercise 2. Step-Up Exercise 3. Squats 4. Lunges 5. Stair Climbing 6. Loaded Walking

functional progressive resistive exercise and designed physical therapy program

Eligibility Criteria

• Age: 6 Years - 10 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• A diagnosis of spastic diplegic CP
• Degree of spasticity ranges from 1+ and 2, according to modified Ashworth scale (MAS)
• The age of the selected children will range from 6 to 10 years old.
• Children are levels II and III according to GMFCS

You may not qualify if:

• Children with visual or auditory problems. 2. Children with severe intellectual disability (IQ less than 65 according to Stanford Binet intelligence scale).

Sponsors & Collaborators

• Cairo University: lead

MeSH Terms

Conditions

Cerebral Palsy

Condition Hierarchy (Ancestors)

Brain Damage, Chronic; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Central Study Contacts

Alaa Alnemr

CONTACT

+201003727467; alaaalnemr28@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant professor at faculty of physical therapy, cairo university

Study Record Dates

• First Submitted: June 23, 2026
• First Posted: June 30, 2026
• Study Start: July 1, 2026
• Primary Completion (Estimated): August 11, 2026
• Study Completion (Estimated): November 9, 2026
• Last Updated: June 30, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share