The Value of a Simple Tool for the Early Detection of Decompensated Heart Failure in People Over 55 on Réunion Island: A Preliminary Study in Hospitals (DEPIST'IC-RUN)

NCT07673562 | Not Yet Recruiting

• 2 other identifiers: 2026/RUN/00042026-A00499-42
• Study Type: observational
• Target: 300
• Locations: 0 countries
• Sites: N/A

Brief Summary

The goal of this study is to assess the discriminatory power of a previously developed tool for detecting decompensated heart failure-which includes, in particular, clinical signs-in a population of patients hospitalized in cardiology units in Réunion. The main question it aims to answer is : Would a simple and rapid screening tool for decompensated heart failure help identify a high probability of this condition in a population hospitalized in a cardiology unit in Réunion? This study includes patients aged 55 and older, who reside in Réunion, who were admitted on an unscheduled basis to the cardiology department at the Réunion University Hospital or the Ouest Réunion Hospital, for any reason (whether as an inpatient or in the intensive care unit) The study is conducted in two phases: Phase 1: Development of the new e-DELPHI consensus-based screening tool Phase 2: Administration of the Déspist'IC-Run early detection tool for decompensated heart failure and performance of the gold standard cardiology examination (RIPH3)

Conditions

Heart Failure

Keywords

Decompensated heart failure; early detection; questionnaire

Outcome Measures

Primary Outcomes (1)

• Estimating the discriminant validity of a tool for detecting decompensated heart failure

  The probability of having decompensated heart failure, as determined by a screening tool in the form of a questionnaire, will be calculated using the equation of a logistic regression model that explains the observed status (dependent variable) as determined by the gold standard test. The gold standard test for establishing a definitive diagnosis of decompensated heart failure will combine three tests: a clinical examination by a cardiologist, a transthoracic Doppler echocardiogram (TTE), and an electrocardiogram.

  "From enrollment to the end of the study, at 6 month

Secondary Outcomes (3)

• Describe the operational phases involved in developing the screening tool.

  From enrolment to the end of the study, at 6 month

• Describe the sociodemographic and clinical characteristics, as well as the lifestyle habits, of the study population.

  From enrollment to the end of the study at 6 months

• Compare the sociodemographic and medical characteristics of this population of patients hospitalized in cardiology with those of other populations of patients with heart failure seen in private practices-whether in cardiology or general practice

  From enrollment to the end of the study at 6 month

Study Arms (1)

Cardiology patients

Patients aged 55 or older admitted to a cardiology unit for any reason

Diagnostic Test: Early Detection Questionnaire

Interventions

Early Detection Questionnaire DIAGNOSTIC_TEST

Questionnaire for the Early Detection of Heart Failure

Cardiology patients

Eligibility Criteria

• Age: 55 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients aged 55 or older who reside on Réunion Island and are hospitalized in the cardiology department of the University Hospital (CHU) or the Centre Hospitalier Ouest Réunion (CHOR)

You may qualify if:

• Patients:
• Aged 55 and older
• Admitted on an unscheduled basis to the cardiology department at the CHU (North and South campuses) and the CHOR for any reason (in general wards or intensive care)
• Residents of Réunion
• Able to read and write French
• Enrolled in a social security program
• Willing to participate in the study

You may not qualify if:

• Patients:
• Who cannot communicate in French
• For whom it is impossible to administer the questionnaire
• For whom the ETT and/or cardiology consultation are impossible
• Who are under guardianship, conservatorship, or judicial protection

Sponsors & Collaborators

• Centre Hospitalier Universitaire de la Réunion: lead

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases

Central Study Contacts

Jérôme CORRE, Dr

CONTACT

+262 262 90 05 52; jerome.corre@chu-reunion.fr

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 18, 2026
• First Posted: June 29, 2026
• Study Start (Estimated): August 12, 2026
• Primary Completion (Estimated): February 1, 2027
• Study Completion (Estimated): February 1, 2027
• Last Updated: June 29, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share