NCT07666867

Brief Summary

Healthcare providers in high-demand clinical settings are at high risk for burnout and secondary traumatic stress due to repeated exposure to patient trauma, which can compromise well-being and quality of care. Compassion-focused cognitive behavioral therapy (CF-CBT) can reduce stress and enhance self-compassion, but traditional delivery is time- and resource-intensive. This project evaluates the feasibility, acceptability, and potential effectiveness of virtual reality (VR)-enhanced CF-CBT specifically adapted for healthcare providers experiencing vicarious trauma. Grounded in Neff's self-compassion framework (emphasizing self-kindness, common humanity, and mindfulness) the VR intervention provides 8 immersive environments where participants can practice compassion-focused skills, engage in procedural learning, and regulate emotional responses in real time. The study will be conducted at UC San Diego Health using a two-arm randomized design comparing VR-enhanced CF-CBT with self-guided compassion-focused CBT/mindfulness exercises delivered without VR. Participants will complete 8 brief VR interventional sessions (approximately 6-10 minutes each) over 4-6 weeks. Outcomes include self-compassion, burnout, and secondary traumatic stress, measured using validated instruments. Feasibility and acceptability will be evaluated through recruitment, retention, session completion, engagement, and participant feedback. Findings will provide preliminary evidence for VR-enhanced compassion-focused interventions as a scalable and accessible approach to supporting healthcare providers' emotional well-being in demanding clinical environments, and will inform future cultural adaptation and implementation in low-resource and conflict-affected healthcare settings such as those in post-war zones.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
52

participants targeted

Target at P25-P50 for not_applicable

Timeline
6mo left

Started Jul 2026

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress15%
Jul 2026Feb 2027

First Submitted

Initial submission to the registry

June 18, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 24, 2026

Completed
7 days until next milestone

Study Start

First participant enrolled

July 1, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2026

Expected
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2027

Last Updated

June 24, 2026

Status Verified

June 1, 2026

Enrollment Period

3 months

First QC Date

June 18, 2026

Last Update Submit

June 18, 2026

Conditions

Keywords

Self-CompassionEmpathyCBTVirtual RealityHealthcare Provider Burnout

Outcome Measures

Primary Outcomes (1)

  • Self-compassion

    Self-compassion will be assessed using the Self-Compassion Scale (SCS), as it reflects a core therapeutic target of the CF-CBT-based techniques

    Baseline assessment (T0), Post-Intervention assessment (T1), and 6 weeks post-intervention assessment (T2)

Secondary Outcomes (2)

  • Burnout

    Baseline assessment (T0), Post-intervention assessment (T1), 6 weeks post-intervention (T2)

  • Secondary Traumatic Stress (STS)

    Baseline assessment (T0), Post-intervention assessment (T1), 6 weeks post-intervention (T2)

Study Arms (2)

Virtual Reality enhanced Compassion Focused Cognitive Behavioral Therapy

ACTIVE COMPARATOR

This arm will receive a fixed number of immersive compassion focused cognitive behavioral therapy sessions delivered via virtual reality headsets.

Behavioral: Compassion focused cognitive behavioral therapy sessions delivered via virtual reality headsets

Control Group

PLACEBO COMPARATOR

This arm will receive compassion focused cognitive behavioral therapy delivered via psychoeducational booklets.

Behavioral: Compassion focused cognitive behavioral therapy app based booklet

Interventions

The intervention group will undergo a fixed number of immersive compassion focused cognitive behavioral therapy sessions delivered via virtual reality headsets.

Also known as: Virtual Reality, CF-CBT
Virtual Reality enhanced Compassion Focused Cognitive Behavioral Therapy

This arm will receive the same order and frequency of compassion focused cognitive behavioral therapy sessions delivered via digital booklets

Also known as: Control
Control Group

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • have at least one year of experience working in a healthcare setting

You may not qualify if:

  • participating in other behavioral interventions that could confound study results
  • auditory or visual impairments that would interfere with VR usage
  • Participants who experience clinically significant VR-related discomfort/motion sickness as assessed by the Simulator Sickness Questionnaire (SSQ)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Burnout, Psychological

Condition Hierarchy (Ancestors)

Stress, PsychologicalBehavioral SymptomsBehavior

Study Officials

  • Wael Al-Delaimy, PhD, MD

    University of California, San Diego

    PRINCIPAL INVESTIGATOR
  • Andre Faro, PhD

    Universidade Federal de Sergipe

    STUDY CHAIR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

June 18, 2026

First Posted

June 24, 2026

Study Start

July 1, 2026

Primary Completion (Estimated)

October 1, 2026

Study Completion (Estimated)

February 1, 2027

Last Updated

June 24, 2026

Record last verified: 2026-06