Preoperative Anxiety and Surgical Fear in Holmium Laser Enucleation of the Prostate and Transurethral Resection of the Prostate Patients With Benign Prostatic Hyperplasia

NCT07663097 | Not Yet Recruiting

• 1 other identifier: 2026-85
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Benign prostatic hyperplasia (BPH) is a common condition in older men and may cause bothersome lower urinary tract symptoms that can negatively affect quality of life. Surgical treatment with Holmium Laser Enucleation of the Prostate (HoLEP) or Transurethral Resection of the Prostate (TURP) is often recommended when medical therapy is insufficient. This prospective observational study aims to evaluate whether preoperative anxiety, depression, and surgical fear influence postoperative functional outcomes, urinary continence, erectile function, and patient satisfaction in patients undergoing HoLEP or TURP for BPH. Participants will complete validated psychological and functional questionnaires before surgery and during postoperative follow-up visits at 1 and 3 months. The study will also assess changes in psychological status after surgery and compare outcomes between HoLEP and TURP patients. The findings may help improve preoperative patient counseling and identify patients who could benefit from additional psychological support before surgery.

Conditions

Benign Prostatic Hyperplasia

Keywords

BPH; HOLEP; TURP; Preoperative anxiety; surgical fear; depression; Patient satisfaction; lower urinary tract symptoms; urinary incontinence; erectile function

Outcome Measures

Primary Outcomes (1)

• Change in International Prostate Symptom Score (IPSS)

  Association between preoperative anxiety levels and postoperative functional improvement measured by changes in International Prostate Symptom Score (IPSS). IPSS scores range from 0 to 35, with higher scores indicating more severe lower urinary tract symptoms. Change from baseline to postoperative 3 months will be evaluated.

  Baseline to 3 months after surgery

Secondary Outcomes (5)

• Change in IIEF-5 Score

  Baseline to 3 months after surgery

• Urinary Incontinence Assessed by ICIQ-SF

  1 and 3 months after surgery

• Change in HADS Score

  Baseline to 3 months after surgery

• Change in STAI Score

  Baseline to 3 months after surgery

• Patient Satisfaction Score

  3 months after surgery

Study Arms (2)

HoLEP Group

Patients with benign prostatic hyperplasia undergoing HoLEP surgery.

Procedure: Holmium Laser Enucleation of the Prostate (HoLEP)

TURP Group

Patients with benign prostatic hyperplasia undergoing TURP surgery.

Procedure: Transurethral Resection of the Prostate (TURP)

Interventions

Holmium Laser Enucleation of the Prostate (HoLEP) PROCEDURE

Standard HoLEP procedure for treatment of benign prostatic hyperplasia.

HoLEP Group

Transurethral Resection of the Prostate (TURP) PROCEDURE

Standard TURP procedure for treatment of benign prostatic hyperplasia.

TURP Group

Eligibility Criteria

• Age: 50 Years+
• Gender Eligibility Details: Only male participants are eligible because benign prostatic hyperplasia (BPH) occurs in males and both HoLEP and TURP are surgical procedures performed for male patients with BPH.
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Male patients aged 50 years or older with benign prostatic hyperplasia (BPH) who are scheduled to undergo Holmium Laser Enucleation of the Prostate (HoLEP) or Transurethral Resection of the Prostate (TURP) at Hitit University Erol Olcok Training and Research Hospital and who provide written informed consent.

You may qualify if:

• Male patients aged 50 years or older
• Diagnosis of benign prostatic hyperplasia (BPH)
• Scheduled to undergo HoLEP or TURP
• Ability to understand and complete study questionnaires
• Provided written informed consent

You may not qualify if:

• History of severe psychiatric disorder
• Active psychiatric treatment
• Neurogenic bladder or neurologic voiding dysfunction
• Diagnosis of prostate cancer
• Previous prostate surgery
• Inability to comply with study procedures or follow-up visits

Sponsors & Collaborators

• Hitit University: lead

Study Sites (1)

Hitit university

Çorum, Çorum, 19030, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Prostatic Hyperplasia; Depression; Patient Satisfaction; Lower Urinary Tract Symptoms; Urinary Incontinence

Interventions

Transurethral Resection of Prostate

Condition Hierarchy (Ancestors)

Prostatic Diseases; Genital Diseases, Male; Genital Diseases; Urogenital Diseases; Male Urogenital Diseases; Behavioral Symptoms; Behavior; Treatment Adherence and Compliance; Health Behavior; Urological Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Urination Disorders; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications

Intervention Hierarchy (Ancestors)

Prostatectomy; Urologic Surgical Procedures, Male; Urologic Surgical Procedures; Urogenital Surgical Procedures; Surgical Procedures, Operative

Central Study Contacts

Metin Kızgın, Araştırma görevlisi Dr.

CONTACT

+90 507 136 20 45; mtnkizgin@gmail.com

Mustafa Serdar Caglayan

CONTACT

05074311951; serdar.09.09@hotmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, Department of Urology

Study Record Dates

• First Submitted: June 17, 2026
• First Posted: June 23, 2026
• Study Start: June 14, 2026
• Primary Completion (Estimated): April 8, 2027
• Study Completion (Estimated): June 8, 2027
• Last Updated: June 26, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)