NCT07662460

Brief Summary

Swimming requires high energy in a short time and involves overcoming water resistance. Besides regular training, swimmers use supplements to enhance performance, correct nutrient deficiencies, and speed recovery. The Australian Institute of Sport (AIS) classifies supplements by evidence level, with nitrate in Group A. Nitrate aids vasodilation and muscle performance via conversion to nitric oxide (NO). About 25% of dietary nitrate converts to nitrite by oral bacteria, then to NO in the stomach-a valuable oxygen-independent pathway. NO improves exercise by enhancing oxygen efficiency, muscle contraction, and affecting type II fibers. Timing, dose, nitrate source, and individual traits influence its effect. Beetroot, rich in nitrate, is practical as juice for storage and consumption. Beetroot gels and juices raise plasma nitrate 1-3 hours post-consumption, effective during 10-17 minute exercises. Some studies found no improvement in short-distance swimming, but others reported dose-dependent benefits. Meta-analyses recommend 5-14.9 mmol nitrate ≥150 minutes before acute exercise, and 5-9.9 mmol for chronic intake. Highly trained athletes may need ≥6-8 mmol NO₃-. JECFA and the European Commission set acceptable daily intake (ADI) at 0-3.7 mg/kg body weight nitrate ion, safe for all ages. No long-term, controlled studies exist on beetroot powder's effect in swimmers. To address this, a randomized, placebo-controlled, triple-blind crossover study was designed to evaluate beetroot powder supplementation's impact on competitive swimmers' performance, potentially contributing valuable knowledge.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
21

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Dec 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 22, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 22, 2026

Completed
10 days until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2026

Completed
15 days until next milestone

First Submitted

Initial submission to the registry

June 16, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 23, 2026

Completed
Last Updated

June 23, 2026

Status Verified

May 1, 2025

Enrollment Period

5 months

First QC Date

June 16, 2026

Last Update Submit

June 19, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Change in 200-meter swim performance time

    The duration (in seconds) required for the participant to complete a 200-meter freestyle swim, measured using a Seiko stopwatch.

    On the 3rd day of each 3-day intervention period (after beetroot or placebo supplementation).

  • Blood lactate concentration

    Blood lactate levels (mmol/L) measured from capillary blood samples collected 3 minutes after completion of 200-meter swim test.

    Immediately post-exercise on the 3rd day of each 3-day intervention period (after beetroot or placebo supplementation).

Secondary Outcomes (4)

  • Visual Analog Scale (VAS) for Perceived Fatigue

    On the 3rd day of each 3-day intervention period (after beetroot or placebo supplementation).

  • Heart Rate Change

    On the 3rd day of each 3-day intervention period (after beetroot or placebo supplementation).

  • Change in Perceived Physical and Cognitive Fatigue Scale (AFBYÖ) Scores

    On the 3rd day of each 3-day intervention period (after beetroot or placebo supplementation).

  • Daily Energy and Nutrient Intake

    Collected during the 24-hour period prior to the 3rd day of each 3-day intervention period (both beetroot or placebo supplementation).

Study Arms (2)

Beetroot then Placebo

EXPERIMENTAL

Participants in this arm will first receive 1,5 grams of beetroot powder contain jelly candy daily for 3 consecutive days. After a 14-day washout period, they will receive placebo jelly candy daily for 3 consecutive days.

Dietary Supplement: Beetroot PowderOther: Placebo

Placebo then Beetroot

PLACEBO COMPARATOR

Participants in this arm will first receive placebo jelly candy daily for 3 consecutive days. After a 14-day washout period, they will receive 1,5 grams of beetroot powder contain jelly candy daily for 3 consecutive days.

Dietary Supplement: Beetroot PowderOther: Placebo

Interventions

Beetroot PowderDIETARY_SUPPLEMENT

1.5 g of beetroot powder (equivalent to 10 mmol nitrate) administered as a jelly candy.

Beetroot then PlaceboPlacebo then Beetroot
PlaceboOTHER

Color-matched, nitrate-free jelly candy.

Beetroot then PlaceboPlacebo then Beetroot

Eligibility Criteria

Age18 Years - 24 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Voluntary participation with parental consent
  • Age range: 18-24 years
  • Participation in a training program for at least 18 hours per week
  • No history of chronic disease
  • Not currently using any sports supplements, food supplements, or medications
  • Not following a special diet

You may not qualify if:

  • Irregular training participation
  • Presence of chronic diseases
  • Failure to cease the use of food supplements one week prior to the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kartal Kosuyolu Yuksek Ihtisas Eah

Istanbul, Kartal, Turkey (Türkiye)

Location

Related Links

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
registered dietitian

Study Record Dates

First Submitted

June 16, 2026

First Posted

June 23, 2026

Study Start

December 22, 2025

Primary Completion

May 22, 2026

Study Completion

June 1, 2026

Last Updated

June 23, 2026

Record last verified: 2025-05

Data Sharing

IPD Sharing
Will not share

Individual participant data (IPD) will not be shared due to concerns regarding participant confidentiality and the small sample size, which may increase the risk of re-identification.

Locations