Effect of Coffee Smelling on Pain, Physiological Parameters and Time to Discharge From Post Anesthesia Care Unit in Patients Undergoing Laparoscopic Cholecystectomy

NCT07437599 | Active Not Recruiting

• 1 other identifier: IstanbulUC-FNHF-CH-01
• Study Type: interventional
• Target: 66
• Locations: 1 country
• Sites: 1

Brief Summary

This research was designed as a randomized controlled trial to determine the effects of coffee sniffing on pain and physiological parameters in patients undergoing cholecystectomy surgery.

Conditions

Cholecystectomy, Laparoscopic

Keywords

Postanesthesia Nursing; Laparoscopic Cholecystectomy; Coffee

Outcome Measures

Primary Outcomes (2)

• Modified Aldrete Score

  The Modified Aldrete Score is a clinical scoring system used to assess a patient's recovery and readiness for discharge from the post-anesthesia care unit (PACU) based on activity, respiration, circulation, consciousness, and oxygen saturation. Ensures objective and standardized assessment of postoperative recovery Reduces risk of premature discharge from PACU Enhances patient safety by identifying respiratory, cardiovascular, or neurological instability Provides measurable criteria for clinical decision-making Commonly, a score of ≥ 9 indicates readiness for PACU discharge.

  This is the period from post-operative time until discharge from the PACU unit. (min. 20/min- max 60/min).

• VAS

  The Visual Analog Scale (VAS) for pain is a simple tool used to measure a patient's pain intensity. It usually consists of a 10-centimeter horizontal line with one end labeled "no pain" and the other end labeled "worst pain imaginable." The patient marks a point on the line that represents their level of pain, and the distance from the "no pain" end is measured to determine a numerical score. VAS is widely used in clinical practice and research because it provides a quick, subjective, and reliable assessment of pain severity.

  This is the period from post-operative time until discharge from the PACU unit. (min. 20/min- max 60/min).

Study Arms (2)

Coffee Smelling Group

EXPERIMENTAL

The patient inhales the scent of coffee for 3-5 minutes using a cotton pad.

Behavioral: Coffee Smell

Placebo Group

PLACEBO COMPARATOR

The patient inhales an empty cotton bag for 3-5 minutes.

Behavioral: Placebo

Interventions

Coffee Smell BEHAVIORAL

The patient inhales the scent of coffee for 3-5 minutes using a cotton pad.

Coffee Smelling Group

Placebo BEHAVIORAL

The patient inhales an empty cotton bag for 3-5 minutes.

Placebo Group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Being 18 years of age or older,
• Having no prior history of surgery,
• Having undergone laparoscopic cholecystectomy surgery,
• Being physically and mentally able to communicate,
• Having received the same anesthesia protocol,
• Having no known allergy or sensitivity to the smell of coffee,
• Being willing and cooperative to smell coffee for the specified duration in the experimental group,
• Providing written consent after being informed about the study,
• Having an ASA I or II rating.

You may not qualify if:

• The following are contraindications for a patient's sense of smell:
• No complications developing during surgery,
• No indication for postoperative intensive care,
• Special circumstances (pregnancy, etc.),
• Being under active treatment for depression, anxiety, or other psychiatric disorders,
• Having anatomical abnormalities that may cause a problem with the sense of smell.

Sponsors & Collaborators

• Istanbul University - Cerrahpasa: lead

Study Sites (1)

Istanbul University Cerrahpasa

Istanbul, Turkey (Türkiye)

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD. Student

Model Details: A randomized controlled trial with intervention and placebo groups.

Study Record Dates

• First Submitted: February 22, 2026
• First Posted: February 27, 2026
• Study Start: February 22, 2026
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): August 30, 2026
• Last Updated: March 3, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)