Reward Sensitivity Digital Intervention for Suicide Risk

NCT07661901 | Recruiting

• 1 other identifier: 45392554 (26-0255)
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to develop and test an app designed to reduce suicide risk and improve emotional well-being in adolescents. The study will test if the app's daily check ins and recommended mood boosting skills will improve the adolescent's overall mood and suicidality. The main question it aims to answer is:

• Is the app practical and acceptable to use daily? In the study, adolescents will:
• Participate in a focus group with other adolescents and provide feedback on the app itself (design, ease of use, etc.).
• Complete surveys and assessments on their mood, thoughts, and experiences.
• Complete assessments about their app experience. In the study, the legal guardian of the adolescent will:
• Participate in a focus group with other adolescents and provide feedback on the app itself (design, ease of use, etc.).
• Complete assessments about their app experience.

Conditions

Suicidal Ideation; Suicidal; Suicidal Thoughts; Digital Health Intervention; Reward Sensitivity; Anhedonia

Keywords

Adolescents; Legal Guardians; Digital; Philadelphia; Suicide; Intervention; Prevention; Dyads; Reward Sensitivity; Anhedonia

Outcome Measures

Primary Outcomes (2)

• Acceptability of Digital Suicide Prevention Intervention

  At least 80% of youth will report in qualitative feedback that the digital suicide prevention intervention is helpful and relevant to their daily lives.

  Day 1 (Focus Group)

• Usability of Digital Suicide Prevention Intervention

  The digital suicide prevention intervention prototype will exceed established usability benchmarks, as measured by the System Usability Scale (SUS; range = 0-100, with higher scores indicating greater perceived usability), with a mean SUS score of at least 70.

  Day 1 (Focus Group)

Interventions

Suicide prevention treatment BEHAVIORAL

Digital just-in-time adaptive intervention to enhance reward sensitivity and reduce suicidal ideation

Also known as: DIGIReward

Eligibility Criteria

• Age: 13 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• ADOLESCENTS
• Aged 13-17 years old
• Recent suicidal ideation
• Access to a smartphone device
• Residing in the Philadelphia metropolitan area
• LEGALGUARDIANS
• They are the legal guardian of an adolescent that meets all study criteria (see above)
• They can read, write, and speak English

You may not qualify if:

• ADOLESCENTS
• Psychotic disorder, including schizophrenia, schizoaffective disorder, or psychotic disorder not otherwise specified, with a past year psychotic episode prior to baseline
• Bipolar disorder I diagnosis, with a past year manic episode prior to baseline
• Imminent suicide risk (e.g., active suicidal ideation with a specific plan and intent)
• LEGALGUARDIANS

Sponsors & Collaborators

• University of Pennsylvania: lead

Study Sites (1)

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

RECRUITING

MeSH Terms

Conditions

Suicidal Ideation; Anhedonia; Suicide

Condition Hierarchy (Ancestors)

Self-Injurious Behavior; Behavioral Symptoms; Behavior; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Marin Kautz, Ph.D.

  University of Pennsylvania

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Sydney Lempert, B.A.

CONTACT

215-746-3337; Sydney.Lempert@Pennmedicine.upenn.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 2, 2026
• First Posted: June 22, 2026
• Study Start: June 1, 2026
• Primary Completion (Estimated): June 1, 2027
• Study Completion (Estimated): September 1, 2027
• Last Updated: June 22, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)