Key Insights

Highlights

Success Rate

94% trial completion (above average)

Published Results

16 trials with published results (19%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

3.6%

3 terminated out of 83 trials

Success Rate

93.8%

+7.2% vs benchmark

Late-Stage Pipeline

13%

11 trials in Phase 3/4

Results Transparency

36%

16 of 45 completed with results

Key Signals

16 with results94% success

Data Visualizations

Phase Distribution

74Total
Not Applicable (47)
P 1 (7)
P 2 (9)
P 3 (6)
P 4 (5)

Trial Status

Completed45
Recruiting20
Unknown5
Not Yet Recruiting4
Active Not Recruiting3
Terminated3

Trial Success Rate

93.8%

Benchmark: 86.5%

Based on 45 completed trials

Clinical Trials (83)

Showing 20 of 20 trials
NCT07637773Not ApplicableRecruiting

Investigating the Efficacy and Mechanisms of Individualized tACS Targeting Anhedonia in Late-Life Depression

NCT06635135Phase 3Terminated

A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure

NCT06829953Not ApplicableRecruitingPrimary

Get ActivE Study for At-risk Youth

NCT06648460Not ApplicableNot Yet Recruiting

Multimodal Differences in Effort-based Decision-Making in Depression

NCT05849038Phase 2Recruiting

Inflammation and Depression in People With HIV

NCT07607938Phase 1Not Yet RecruitingPrimary

Psilocybin as a Novel Therapy for Residual Anhedonia

NCT06230757Phase 2Completed

Psilocybin for Treatment-Resistant Depression

NCT05991713Not ApplicableRecruiting

Geolocation Positional System (GPS) Experience

NCT07319143Not ApplicableRecruiting

The Effect of Transcranial Direct Current Stimulation (tDCS) in Improving Emotion Health

NCT06096740Not ApplicableRecruiting

Psychotherapy Effects on Reward Processing in PTSD

NCT07078227Recruiting

Long-term Follow-up of Depressive Disorders in Psychiatric Care

NCT05282277Phase 4Recruiting

Examining the Effects of Estradiol on Neural and Molecular Response to Reward

NCT05825235Phase 3CompletedPrimary

Long-term Efficacy of Pramipexole in Anhedonic Depression

NCT05355337Phase 3Completed

Pramipexole for Anhedonic Depression

NCT06391593Phase 2Completed

PD, PK, and Safety of ALTO-203 in Patients With MDD

NCT06776991Not ApplicableRecruiting

Reward Processing and Exposure Therapy for Social Anxiety Disorder

NCT07146503Recruiting

Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression

NCT07493369Not ApplicableActive Not RecruitingPrimary

Positive Affect Treatment for Spanish-Speaking Individuals

NCT07490353Phase 1Recruiting

Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects

NCT05487885Phase 4Completed

Anhedonia, Development, and Emotions: Phenotyping and Therapeutics

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