Key Insights

Highlights

Success Rate

93% trial completion (above average)

Published Results

15 trials with published results (19%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

3.7%

3 terminated out of 81 trials

Success Rate

93.3%

+6.8% vs benchmark

Late-Stage Pipeline

14%

11 trials in Phase 3/4

Results Transparency

36%

15 of 42 completed with results

Key Signals

15 with results93% success

Data Visualizations

Phase Distribution

72Total
Not Applicable (46)
P 1 (6)
P 2 (9)
P 3 (6)
P 4 (5)

Trial Status

Completed42
Recruiting19
Active Not Recruiting5
Unknown5
Not Yet Recruiting4
Terminated3

Trial Success Rate

93.3%

Benchmark: 86.5%

Based on 42 completed trials

Clinical Trials (81)

Showing 20 of 20 trials
NCT06776991Not ApplicableRecruiting

Reward Processing and Exposure Therapy for Social Anxiety Disorder

NCT07146503Recruiting

Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression

NCT07493369Not ApplicableActive Not RecruitingPrimary

Positive Affect Treatment for Spanish-Speaking Individuals

NCT07490353Phase 1Recruiting

Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects

NCT06829953Not ApplicableRecruitingPrimary

Get ActivE Study for At-risk Youth

NCT05487885Phase 4Completed

Anhedonia, Development, and Emotions: Phenotyping and Therapeutics

NCT06635135Phase 3Terminated

A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure

NCT06132581Not ApplicableRecruiting

Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic Depression

NCT05920252Not ApplicableRecruiting

A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide

NCT05988138Not ApplicableCompletedPrimary

Prevention of Anhedonia in Children

NCT05240352Not ApplicableRecruitingPrimary

Developing Brain Imaging Analysis Expertise for Personalizing Transcranial Electric Stimulation in Anhedonia Treatment of Patients With Bipolar Depression

NCT06514742Phase 3Terminated

A Study of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy and Long-term Extension Treatment With Aticaprant

NCT05550532Phase 3Completed

A Study of Aticaprant 10 Milligrams (mg) as Adjunctive Therapy in Adult Participants With MDD With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy

NCT05537285Not ApplicableCompleted

Individualized Neuromodulation for Anhedonic Depression

NCT07348666Not ApplicableNot Yet Recruiting

A Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents

NCT06075771Phase 4RecruitingPrimary

Dopaminergic Therapy for Anhedonia - 2

NCT03848715Phase 1CompletedPrimary

Sleep and Healthy Aging Research on Depression for Younger Women

NCT06230757Phase 2Active Not Recruiting

Psilocybin for Treatment-Resistant Depression

NCT06665620Not ApplicableActive Not Recruiting

Optimizing a Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents

NCT07155941Not ApplicableRecruitingPrimary

Ecological Momentary Intervention for Reward in Anhedonia

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