Study on the Effect of Edible Mastication Training Colloid Intervention of Oral Muscle Training in Patients of Sarcopenia

NCT07658599 | Completed

• 2 other identifiers: 202301544A3C601ZRRPF3N0061
• Study Type: interventional
• Target: 68
• Locations: 1 country
• Sites: 1

Brief Summary

The main purpose of this study is to screen middle-aged and elderly (≧ 45 years old) individuals at high risk of sarcopenia and sarcopenia, and to investigate whether sarcopenia can improve dental bite force and tongue pressure in middle-aged and elderly sarcopenia subjects when given edible chewing training colloidal intervention.This trial method will recruit 120 subjects for oral strength training twice a day for 8 weeks, and compare the difference in chewing level between the subjects using the oral strength training intervention and the oral strength training intervention before and after the test. The differences between dental occlusal force and tongue pressure after training were also explored. The experiment mainly evaluated the scales related to dental occlusal force, tongue pressure, and quality of life, because the quality of oral muscles is highly correlated with the diet and lifestyle of the elderly, and also affects the physical health and mobility of the elderly. Although the loss of muscle mass due to aging may be unavoidable, appropriate oral strength training intervention may delay or modify the adverse effects of sarcopenia and improve quality of life in sarcopenia subjects.

Conditions

Non-sarcopenic Subjects; Possible Sarcopenia; Sarcopenia (With Low ASM by BIM)

Keywords

sarcopenia; chewing; oral strength training; muscle strength

Outcome Measures

Primary Outcomes (1)

• Based on the results of empirical research on sarcopenia in Asian countries, a diagnostic consensus was established.

  * The cut-off point for abnormal grip strength is less than 28 kg for men and less than 18 kg for women * 6-meter walking speed less than 1.0 second/meter * 5-time chair stand test greater than or equal to 12 seconds * Short physical performance battery, SPPB greater than or equal to 9 points

  From Intervention to Experiment Completion (eight weeks)

Study Arms (1)

NON

OTHER

NON

Behavioral: oral muscle strength training

Interventions

oral muscle strength training BEHAVIORAL

Oral muscle strength tests are conducted the day before the intervention and during the eighth week after the intervention.

Also known as: NON

NON

Eligibility Criteria

• Age: 45 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years old (inclusive) or older
• The general public or the institution has stayed for more than 3 months (inclusive)
• Those who accept the experimental design and intervention, and are willing to sign the consent form
• The source of the diet is that you can eat by mouth independently
• Those who meet the diagnosis definition of sarcopenia by the Asian Sarcopenia Consensus Association
• No history of chewing and swallowing

You may not qualify if:

• Those who may have allergic or uncomfortable reactions to edible chewing colloids (honey flavor)
• Feeders
• Other dietitians who cannot complete this researcher
• Those who cause discomfort when chewing (such as temporomandibular joint pain, oral ulcers, severe tooth decay, etc.)
• Those who report choking and coughing when chewing

Sponsors & Collaborators

• Chang Gung University of Science and Technology: lead

Study Sites (1)

Chang Gung University of Science and Technology

Taoyuan, Taiwan

Location

MeSH Terms

Conditions

Sarcopenia

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 10, 2026
• First Posted: June 22, 2026
• Study Start: March 1, 2024
• Primary Completion: April 25, 2024
• Study Completion: April 25, 2024
• Last Updated: June 22, 2026

Record last verified: 2026-06

Locations

TW (1)