Association Between Oral Hypofunction, Sarcopenia and Social Frailty in Community-dwelling Older Adults

NCT07658625 | Completed

• 2 other identifiers: 202500861A3ZRRPF3Q0061
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Previous studies have provided a preliminary understanding of the likelihood of sarcopenia and the prevalence of sarcopenia in the elderly in the community. due to the interaction between physiological and social factors, this study aims to conduct a correlation study on muscle mass, oral function and social frailty in the elderly living in the community. This study，the Makizako social frailty screening index questionnaire and the Tilburg Frailty Indicator will be used to assess the social frailty status of the study participants. Correlation analysis with sarcopenia and oral dysfunction was also conducted to better understand the interaction between nutrition, physiology, and social connection in the elderly, which will be helpful for formulating relevant policies and promoting healthy aging in the future in extremely elderly countries.

Conditions

Non Sarcopenic Subjects; Possible Sarcopenia; Sarcopenia(With Low ASM by BIM)

Keywords

Sarcopenia; Poor oral function; Social weakness; chew; Nutrition

Outcome Measures

Primary Outcomes (1)

• Based on the results of empirical research on sarcopenia in Asian countries, a diagnostic consensus was established.

  * The cut-off point for abnormal grip strength is less than 28 kg for men and less than 18 kg for women * 6-meter walking speed less than 1.0 second/meter * 5-time chair stand test greater than or equal to 12 seconds * Short physical performance battery, SPPB greater than or equal to 9 points The above will be combined to determine whether sarcopenia is possible.

  Baseline

Study Arms (2)

Group A

Possible sarcopenia

Other: Non interventional study

Group B

Non-possible sarcopenia

Other: Non interventional study

Interventions

Non interventional study OTHER

NON

Group A; Group B

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Care centers in Taoyuan City and various districts of New Taipei City

You may qualify if:

• years old or above
• general public or institutionalized for 3 months or more
• those who accept the experimental design and are willing to sign the consent form
• dietary sources are oral intake
• those who are diagnosed as having possible sarcopenia by researchers
• years old or above
• general public or institutionalized for 3 months or more
• those who accept the experimental design and are willing to sign the consent form
• dietary sources are oral intake
• those who were determined by researchers to be non-probable sarcopenia

You may not qualify if:

• comorbidities, critical illness, pre- and post-major surgery, cancer, renal failure, liver failure, kidney disease, liver disease, malignant tumors within the past five years, inflammatory conditions (c-reactive protein \>10mg/dL)
• severely malnourished people
• long-term force-feeding

Sponsors & Collaborators

• Chang Gung University of Science and Technology: lead

Study Sites (1)

Chang Gung University of Science and Technology

Taoyuan, Taiwan

Location

MeSH Terms

Conditions

Sarcopenia

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 10, 2026
• First Posted: June 22, 2026
• Study Start: November 14, 2025
• Primary Completion: June 4, 2026
• Study Completion: June 4, 2026
• Last Updated: June 22, 2026

Record last verified: 2026-06

Locations

TW (1)