NCT07656662

Brief Summary

Horizontal alveolar ridge deficiencies may prevent the placement of dental implants and often require bone augmentation procedures before implant treatment. Two techniques commonly used for horizontal ridge augmentation are the Split Box Technique and the Split Bone Block Technique. This retrospective study included patients treated at Marmara University Faculty of Dentistry between January 2014 and January 2026. Radiographic records were reviewed to evaluate bone gain after augmentation and the stability of the augmented bone during long-term follow-up. Implant survival after prosthetic rehabilitation was also assessed. The purpose of this study was to compare the long-term outcomes of the Split Box Technique and the Split Bone Block Technique in terms of bone gain, bone stability, and implant survival.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
31

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jan 2014

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2014

Completed
12 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2026

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

June 5, 2026

Completed
13 days until next milestone

First Posted

Study publicly available on registry

June 18, 2026

Completed
Last Updated

June 18, 2026

Status Verified

June 1, 2026

Enrollment Period

12 years

First QC Date

June 5, 2026

Last Update Submit

June 16, 2026

Conditions

Keywords

Split Box TechniqueSplit Bone Block TechniqueHorizontal Ridge AugmentationDental ImplantsBone ResorptionImplant SurvivalCBCT

Outcome Measures

Primary Outcomes (1)

  • Long-Term Horizontal Bone Gain

    Overall change in horizontal alveolar ridge width from baseline to long-term follow-up after prosthetic loading, measured on CBCT images.

    From baseline (preoperative CBCT) to long-term follow-up after prosthetic loading(average follow-up: 4.2 years)

Secondary Outcomes (4)

  • Implant Survival Rate

    From implant placement through study completion (average follow-up: 4.2 years)

  • Postoperative Complications

    From augmentation surgery through study completion (average follow-up: 4.2 years)

  • Long-Term Bone Resorption

    From 6 months after augmentation surgery to long-term follow-up after prosthetic loading (average follow-up: 4.2 years)

  • Horizontal Bone Gain

    From baseline (preoperative CBCT) to 6 months after augmentation surgery

Study Arms (2)

Split Bone Block Technique (SBBT)

Patients who underwent horizontal alveolar ridge augmentation using the Split Bone Block Technique.

Procedure: Split Bone Block Technique

Split Box Technique (SBT)

Patients who underwent horizontal alveolar ridge augmentation using the Split Box Technique.

Procedure: Split Box Technique

Interventions

Autogenous horizontal ridge augmentation procedure using cortical bone plates harvested from the mandibular ramus to reconstruct deficient alveolar ridges prior to implant placement.

Also known as: SBBT
Split Bone Block Technique (SBBT)

Autogenous horizontal ridge augmentation procedure involving mobilization and fixation of a buccal bone segment to increase horizontal ridge width prior to implant placement.

Also known as: SBT
Split Box Technique (SBT)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study population consisted of adult patients with horizontal alveolar ridge deficiencies who underwent horizontal ridge augmentation using either the Split Box Technique or the Split Bone Block Technique before implant placement. Patients were treated at Marmara University Faculty of Dentistry between January 2014 and January 2026 and had complete clinical records and CBCT imaging available for retrospective evaluation.

You may qualify if:

  • Age ≥18 years.
  • Patients with horizontal alveolar ridge deficiency requiring horizontal ridge augmentation before implant placement.
  • Patients treated with either the Split Box Technique (SBT) or Split Bone Block Technique (SBBT) at Marmara University Faculty of Dentistry between January 2014 and January 2026.
  • Availability of complete radiographic records, including CBCT scans obtained preoperatively (T0), 6 months after augmentation (T1), and during long-term follow-up after prosthetic loading (T2).
  • Availability of complete clinical records and follow-up data.

You may not qualify if:

  • Incomplete clinical or radiographic records.
  • Patients lost to follow-up.
  • Presence of uncontrolled systemic diseases or conditions known to adversely affect bone healing.
  • Use of medications known to interfere with bone metabolism or healing.
  • Active infection at the augmentation site or complications that altered the planned treatment protocol.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Marmara University Faculty of Dentistry, Department of Oral and Maxillofacial Surgery

Istanbul, Istanbul, 34854, Turkey (Türkiye)

Location

Related Publications (2)

  • Dergin G, Kirac Can SB, Can S. A novel approach for horizontal augmentation with split box: A method that combines split bone block and ridge split techniques. J Stomatol Oral Maxillofac Surg. 2024 Dec;125(6):101790. doi: 10.1016/j.jormas.2024.101790. Epub 2024 Feb 1.

  • Khoury F, Hanser T. Mandibular bone block harvesting from the retromolar region: a 10-year prospective clinical study. Int J Oral Maxillofac Implants. 2015 May-Jun;30(3):688-97. doi: 10.11607/jomi.4117.

MeSH Terms

Conditions

Bone Resorption

Condition Hierarchy (Ancestors)

Bone DiseasesMusculoskeletal Diseases

Study Officials

  • Guhan Dergin, DDS, PhD

    Marmara University Faculty of Dentistry

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 5, 2026

First Posted

June 18, 2026

Study Start

January 1, 2014

Primary Completion

January 1, 2026

Study Completion

January 1, 2026

Last Updated

June 18, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will not share

Locations