SPSIP Versus RISS Block in Volume-Preserving VATS

NCT07655336 | Not Yet Recruiting

• 2 other identifiers: 26-AKD-1502025-KAEK-47
• Study Type: interventional
• Target: 84
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective randomized controlled study aims to compare the effects of Serratus Posterior Superior Intercostal Plane (SPSIP) block and Rhomboid Intercostal and Subserratus (RISS) block on postoperative pain, respiratory function, and recovery quality in patients undergoing volume-preserving video-assisted thoracoscopic surgery (VATS). Eighty-four patients will be randomized in a 1:1 ratio to receive either SPSIP block or RISS block. The primary outcome is the incidence of somatic pain at the chest drain insertion site at postoperative 2 hours. Secondary outcomes include pain scores, opioid consumption, quality of recovery, diaphragmatic function, pulmonary function, rescue analgesic requirements, postoperative nausea and vomiting, and block-related complications.

Conditions

Postoperative Pain; Thoracic Surgery

Keywords

Video-Assisted Thoracic Surgery; VATS; Serratus Posterior Superior Intercostal Plane Block; Rhomboid Intercostal and Subserratus Block; Diaphragmatic Excursion; Peak Expiratory Flow

Outcome Measures

Primary Outcomes (1)

• Incidence of Somatic Pain at Chest Tube Insertion Site

  Incidence of somatic pain localized at the chest tube insertion site, defined as sharp localized pain aggravated by coughing or deep inspiration, recorded as present or absent.

  Postoperative 2 hours

Secondary Outcomes (7)

• Postoperative Pain Scores at Rest

  Postoperative 2, 6, 12, and 24 hours

• Postoperative Pain Scores During Movement

  Postoperative 2, 6, 12, and 24 hours

• Total Intravenous Morphine Consumption

  Postoperative 24 hours

• Interval Intravenous Morphine Consumption

  Postoperative 0-8, 8-16, and 16-24 hours

• Right Hemidiaphragm Excursion

  Preoperative and postoperative 6 hours

Study Arms (2)

SPSIP Block Group

EXPERIMENTAL

Patients will receive an ultrasound-guided Serratus Posterior Superior Intercostal Plane (SPSIP) block before induction of general anesthesia for postoperative analgesia after video-assisted thoracic surgery (VATS).

Procedure: Serratus posterior superior intercostal plane block

RISS Block Group

EXPERIMENTAL

Patients will receive an ultrasound-guided Rhomboid Intercostal and Subserratus (RISS) block before induction of general anesthesia for postoperative analgesia after video-assisted thoracic surgery (VATS).

Procedure: Rhomboid Intercostal and Subserratus Block

Interventions

Serratus posterior superior intercostal plane block PROCEDURE

Ultrasound-guided Serratus Posterior Superior Intercostal Plane (SPSIP) block performed before induction of general anesthesia using local anesthetic for postoperative analgesia in patients undergoing video-assisted thoracic surgery.

SPSIP Block Group

Rhomboid Intercostal and Subserratus Block PROCEDURE

Ultrasound-guided Rhomboid Intercostal and Subserratus (RISS) block performed before induction of general anesthesia using local anesthetic for postoperative analgesia in patients undergoing video-assisted thoracic surgery.

RISS Block Group

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients scheduled for elective biportal video-assisted thoracoscopic surgery (VATS) with lung parenchyma-preserving thoracic procedures under general anesthesia
• American Society of Anesthesiologists (ASA) physical status I-III
• Age between 18 and 75 years
• Provision of written informed consent

You may not qualify if:

• Use of anticoagulant or antiplatelet therapy
• Bleeding diathesis
• Known allergy to local anesthetics
• Infection at the planned block site
• Severe chronic pulmonary disease or advanced respiratory failure (e.g., severe COPD or restrictive lung disease)
• Cognitive impairment preventing reliable NRS assessment
• Pregnancy or lactation
• Chronic opioid use (regular use for ≥3 months)
• Severe hepatic or renal failure
• Refusal to participate
• Technical failure or unsuccessful regional block
• Conversion to open thoracotomy during surgery

Sponsors & Collaborators

• Ferit Yetik: lead
• Bursa Sehir Hastanesi: collaborator

Study Sites (1)

Bursa City Hospital

Bursa, Nilüfer, 16100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Central Study Contacts

Yusuf Alan

CONTACT

+905396210977; dryusufalan@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: Participants, outcome assessors, and investigators responsible for postoperative data collection and analysis will remain blinded to group allocation throughout the study period. Block procedures will be performed by an anesthesiologist not involved in postoperative assessments.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: MD

Model Details: Prospective, randomized, double-blind, parallel-group clinical trial comparing Serratus Posterior Superior Intercostal Plane (SPSIP) block and Rhomboid Intercostal and Subserratus (RISS) block for postoperative analgesia after video-assisted thoracic surgery (VATS). Eighty-four participants will be randomized in a 1:1 ratio to receive SPSIP block or RISS block.

Study Record Dates

• First Submitted: June 12, 2026
• First Posted: June 17, 2026
• Study Start: June 1, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: June 17, 2026

Record last verified: 2026-06

Locations

TU (1)