Effect of Adding Augmented Cues /Hand Stroke Patient

NCT07654582 | Not Yet Recruiting

• 1 other identifier: P.T.REC/012/006310
• Study Type: interventional
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to investigate the effect of adding augmented cues to conventional physical therapy intervention on hand function in patients with post-stroke hemiparesis. Fifty patients with subacute ischemic stroke will be randomly assigned to either a study group receiving augmented cue-based training in addition to conventional physical therapy or a control group receiving conventional physical therapy alone. Hand function will be assessed before and after the intervention period using the Nine-Hole Peg Test (NHPT), hand grip strength measured by a dynamometer, and pressure pain threshold measured by a pressure algometer. The findings of this study may provide evidence regarding the effectiveness of augmented cue-based rehabilitation strategies in improving hand function after stroke.

Conditions

Ischemic Stroke

Keywords

augmented cues; stroke rehab; hand function; musical gloves; upper extremity rehabilition; grip strenght

Outcome Measures

Primary Outcomes (1)

• Nine-Hole peg Test (NHPT)

  Manual dexterity assessed using the Nine-Hole Peg Test. The time required to place and remove nine pegs will be recorded in seconds. Lower scores indicate better hand dexterity.

  Baseline and after 8 weeks of treatment

Secondary Outcomes (2)

• hand grip strength

  Baseline and after 8 weeks of treatment

• pressure pain threshold

  Baseline and after 8 weeks of treatment

Study Arms (2)

control group

ACTIVE COMPARATOR

Participants will receive a conventional physical therapy program for hand rehabilitation after stroke. Treatment will be administered three times per week for eight weeks (24 sessions), with each session lasting 60 minutes and including range of motion exercises, strengthening exercises, stretching, and task-oriented hand training.

Other: Conventional physical therapy

musical gloves

EXPERIMENTAL

articipants will receive the same conventional physical therapy program provided to the control group in addition to MusicGlove training. Treatment will be administered three times per week for eight weeks (24 sessions). MusicGlove will provide augmented visual, auditory, and performance feedback during task-specific hand training.

Other: Conventional physical therapy; Device: musicgloves training

Interventions

Conventional physical therapy OTHER

Participants will receive a conventional physical therapy program for upper limb and hand rehabilitation after stroke. The program includes stretching exercises, range of motion exercises, strengthening exercises, and task-oriented hand training. Treatment will be provided three times per week for eight weeks (24 sessions).

control group; musical gloves

musicgloves training DEVICE

MusicGlove is a sensor-based rehabilitation device that provides augmented visual, auditory, and performance feedback during task-specific hand exercises. Participants perform repetitive thumb-to-finger opposition and grasping movements synchronized with computer-based musical activities. Training will be provided in addition to conventional physical therapy three times per week for eight weeks.

musical gloves

Eligibility Criteria

• Age: 40 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• \- Male and female patients.
• Age between 40 and 60 years.
• First-ever subacute ischemic stroke.
• Time since stroke between 6 weeks and 6 months.
• Unilateral upper limb involvement.
• Able to understand and follow verbal instructions.
• Medically stable and able to participate in the rehabilitation program.
• Willing to provide informed consent.

You may not qualify if:

• \- Hemorrhagic stroke.
• Bilateral stroke involvement.
• Severe cognitive impairment or severe aphasia interfering with participation.
• Severe visual or auditory deficits affecting training.
• Severe upper limb spasticity that prevents hand training.
• Other neurological disorders affecting upper limb function.
• Severe musculoskeletal disorders of the upper limb.
• Participation in another rehabilitation trial during the study period.
• Unstable cardiovascular or medical conditions.

Sponsors & Collaborators

• Cairo University: lead

MeSH Terms

Conditions

Ischemic Stroke

Condition Hierarchy (Ancestors)

Stroke; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Moshera H Darwish, PHD

  Professor of Physical Therapy for Neurology and Neurosurgery Faculty of Physical Therapy Cairo University

  STUDY CHAIR

• mariam m elsayed, phd

  Lecturer in department of physical Therapy for Neurology and Neurosurgery Faculty of physical therapy Cairo University

  STUDY DIRECTOR

• Essam M Abdulwahab, PHD

  Professor of Neurology Faculty of Medicine Al-Azhar university

  STUDY DIRECTOR

Central Study Contacts

Mostafa abdullah ahmed, MD

CONTACT

00201095052373; dr.mostafa.abdullah.abdelaziem@gmail.com

mariam mohamed elsayed, phd

CONTACT

002010950505529; mariamelanany5@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident

Study Record Dates

• First Submitted: June 13, 2026
• First Posted: June 17, 2026
• Study Start (Estimated): August 1, 2026
• Primary Completion (Estimated): August 1, 2027
• Study Completion (Estimated): August 1, 2027
• Last Updated: June 17, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share