The Effect of Low Intensity With BFR on Stroke Patients

NCT07292675 | Completed DMC

• 1 other identifier: P.T.REC/012/005961
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

To compare the effects of low-intensity resistance training with blood flow restriction (BFR) versus traditional resistance training on lower limb isokinetic torque and dynamic balance in ischemic stroke survivors.

Conditions

Ischemic Stroke

Keywords

BFR , Stroke

Outcome Measures

Primary Outcomes (1)

• Isokinetic torque

  Baseline

Study Arms (2)

Study group

EXPERIMENTAL

Study group will receive low-intensity BFR resistance training

Other: low-intensity resistance training with blood flow restriction

Control group

ACTIVE COMPARATOR

Control group will receive high intensity resistance training

Other: High intensity resistance training

Interventions

High intensity resistance training OTHER

High-intensity quadriceps training in stroke patients focuses on using 60-80% of 1RM to improve strength, motor unit recruitment, and functional mobility. Exercises such as loaded sit-to-stand, leg press, and step-ups are commonly used to target the quadriceps safely. Training intensity is guided by a perceived exertion of 7-9/10 while maintaining proper supervision to prevent falls. This approach enhances knee stability, gait efficiency, and overall functional independence.

Control group

low-intensity resistance training with blood flow restriction OTHER

"Low-Intensity" BFR Means (for Quads) It involves resistance 20-30% 1RM combined with partial arterial + full venous restriction using a cuff placed on the proximal thigh.

Study group

Eligibility Criteria

• Age: 30 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• First-ever ischemic stroke (3-12 months post-stroke)
• Aged 30-40 years
• Can walk independently or with an aid
• Medically stable and able to follow instructions

You may not qualify if:

• Hemorrhagic stroke
• Deep vein thrombosis or peripheral vascular disease
• Orthopedic conditions affecting lower limb
• Severe cognitive impairment or uncontrolled hypertension

Sponsors & Collaborators

• Delta University for Science and Technology: lead

Study Sites (1)

Private Clinic

Cairo, Egypt

Location

MeSH Terms

Conditions

Ischemic Stroke; Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: The patients in control group will receive high intensity resistance training
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer

Model Details: Groups: * Group A: Low-intensity BFR resistance training * Group B: Traditional resistance training

Study Record Dates

• First Submitted: December 6, 2025
• First Posted: December 18, 2025
• Study Start: July 13, 2025
• Primary Completion: September 13, 2025
• Study Completion: September 13, 2025
• Last Updated: August 13, 2026

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)