NCT07654101

Brief Summary

evaluate whether hand-grip ball exercises reduce thrombosis and occlusions of Midline catheters in hospitalized patients.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
840

participants targeted

Target at P75+ for not_applicable

Timeline
14mo left

Started Jul 2026

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 11, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 17, 2026

Completed
19 days until next milestone

Study Start

First participant enrolled

July 6, 2026

Expected
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2027

4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2027

Last Updated

June 17, 2026

Status Verified

June 1, 2026

Enrollment Period

10 months

First QC Date

June 11, 2026

Last Update Submit

June 11, 2026

Conditions

Midline Catheter

Keywords

midlineocclusionhandgrip

Outcome Measures

Primary Outcomes (1)

  • To compare the effectiveness of a structured upper-limb exercise program versus usual care in reducing the incidence of Midline catheter-related thrombosis/occlusions in a population of hospitalized patients.

    Incidence of Midline thrombosis (%) confirmed by ultrasound.

    from enrollment until catether removal

Study Arms (2)

standard

NO INTERVENTION

usual care

handgrip

EXPERIMENTAL

use of handgrip exercises in patients with midline catether

Other: handgrip

Interventions

handgripOTHER

handgrip in patients with midline catethers

handgrip

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Midline catheter insertion for planned intravenous therapy lasting ≥ 7 days. Age between 18 and 70 years. Catheter inserted in the upper limb (forearm). Ability to understand and perform hand exercises with the limb bearing the venous catheter.
  • Written informed consent.

You may not qualify if:

  • Pre-existing superficial or deep venous thrombosis of the limb used for the Midline catheter.
  • Limb injuries or amputations. Motor or neurological impairment of the hand. Life expectancy \< 7 days. Cognitive impairment/delirium. Medical contraindications to active upper-limb movement.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Bites and Stings

Condition Hierarchy (Ancestors)

PoisoningChemically-Induced DisordersWounds and Injuries

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PI Degan Mario

Study Record Dates

First Submitted

June 11, 2026

First Posted

June 17, 2026

Study Start (Estimated)

July 6, 2026

Primary Completion (Estimated)

May 1, 2027

Study Completion (Estimated)

September 1, 2027

Last Updated

June 17, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will not share