The Effect of Foot Massage With a Massage Roller on Chemotherapy-Related Neuropathic Pain

NCT07650864 | Active Not Recruiting

• 1 other identifier: TSA-2025-16152
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Chemotherapy-related neuropathic pain is experienced by 30-40% of cancer patients. This pain significantly reduces the quality of life and overall well-being of patients battling cancer. Studies widely acknowledge that standardizing neuropathic pain assessment leads to improved patient outcomes. Our project, which we believe will add a different dimension to nursing care for cancer patients, aims to reduce chemotherapy-related neuropathic pain experienced by cancer patients through foot massage. The study population will consist of male and female cancer patients with chemotherapy-related neuropathic pain (VAS ≥ 4/10), over 18 years of age, who are actively undergoing treatment at the Medical Oncology Clinics of Atatürk University Research Hospital between February 1, 2026 and June 30, 2026, and who are not scheduled for surgical procedures during the research period. Accordingly, the minimum number of participants required for the study has been determined as 52. To reduce the risk of possible losses, withdrawals, or missing data during the research process, it is planned to include more participants than the calculated sample size. Within the scope of the research, the Neuropathic Pain Scale (S-LANSS) will be used to determine the presence of neuropathic pain in patients, and the VAS will be used to determine the severity of the pain. After the pre-test is completed, the control group will continue with routine treatment and care in the clinic. The intervention group will receive routine treatment and care, as well as foot massage using a foot massage roller for a total of 30 minutes twice a day. This intervention in the intervention group is planned to continue for 3 weeks. During this period, no other treatment will be applied to patients for neuropathic pain. The fact that only 3 small-scale studies, including one case report, were found in the literature review on this subject, the multidisciplinary collaboration in planning this study, and the expectation that it will offer practical solutions for chemotherapy-related neuropathic pain highlight the originality of the study. It is expected that the results obtained will provide evidence-based contributions to nursing care, support holistic approaches to improving patient comfort, and develop a viable intervention model for healthcare professionals.

Conditions

Neuropathic Pain; Chemotherapy Induced Pain Neuropathy

Outcome Measures

Primary Outcomes (1)

• Pain score

  pain score vas\<6

  3 weeks

Study Arms (2)

wooden massage roller

EXPERIMENTAL

Other: Roller Massage

ıce therapy

ACTIVE COMPARATOR

Other: Ice therapy

Interventions

Roller Massage OTHER

intervention group

wooden massage roller

Ice therapy OTHER

control group

ıce therapy

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• ≥18 years of age
• receiving takzan and platinum group chemotherapy,
• not receiving oxoplatin treatment
• vas pain ≥ 6
• no surgical treatment plan
• voluntary participation

You may not qualify if:

• psychiatric disorder
• treatments other than chemotherapy
• receiving oxoplatin treatment
• communication disorder
• planned surgical procedure

Sponsors & Collaborators

• Ataturk University: lead

Study Sites (1)

Atatürk Üniversitesi

Erzurum, Erzurum, 25080, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Neuralgia

Interventions

Ice

Condition Hierarchy (Ancestors)

Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Water; Hydroxides; Alkalies; Inorganic Chemicals; Anions; Ions; Electrolytes; Oxides; Oxygen Compounds; Environment; Ecological and Environmental Phenomena; Biological Phenomena; Weather; Meteorological Concepts; Environment and Public Health

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assist. Prof. Dr.

Study Record Dates

• First Submitted: June 11, 2026
• First Posted: June 16, 2026
• Study Start: February 1, 2026
• Primary Completion: June 30, 2026
• Study Completion: July 30, 2026
• Last Updated: June 16, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)