Neurodynamic Mobilization for Cervical Radiculopathy

NCT07643701 | Completed

• 2 other identifiers: LGU-DPT-RCT-2024-01pk4fs
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Cervical radiculopathy is a condition caused by compression or irritation of cervical nerve roots, leading to neck pain, arm pain, sensory disturbances, and functional limitations. This randomized controlled trial evaluated whether adding neurodynamic mobilization to conventional physiotherapy improves pain intensity and functional disability in individuals with cervical radiculopathy. Participants received either conventional physiotherapy alone or conventional physiotherapy combined with neurodynamic mobilization over a 5-week treatment period.

Conditions

Cervical Radiculopathy

Outcome Measures

Primary Outcomes (1)

• Pain Intensity

  Pain intensity will be assessed using the Visual Analogue Scale (VAS), a validated self-reported measure of pain severity. The scale ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicate greater pain intensity.

  Baseline and after 5 weeks of intervention.

Secondary Outcomes (1)

• Functional Disability

  Baseline and after 5 weeks of intervention.

Study Arms (2)

Conventional Physiotherapy

EXPERIMENTAL

Participants received conventional physiotherapy including therapeutic exercises, manual therapy, and physical modalities aimed at reducing pain and improving function.

Other: conventional physiotherapy

Conventional Physiotherapy + Neurodynamic Mobilization

EXPERIMENTAL

Participants received conventional physiotherapy including therapeutic exercises, manual therapy, and physical modalities aimed at reducing pain and improving function. In addition, neurodynamic mobilization techniques targeting cervical nerve roots were applied to improve neural mobility and reduce mechanosensitivity. The intervention was delivered over 5 weeks, with a total of 10 sessions. Techniques included neurodynamic sliding mobilization performed within pain-free or low-pain ranges, individually adapted to patient symptoms.

Other: neurodynamic mobilization; Other: conventional physiotherapy

Interventions

conventional physiotherapy OTHER

Conventional physiotherapy consisted of a standardized rehabilitation program including therapeutic exercises, manual therapy techniques, and physical modalities. Therapeutic exercises focused on cervical range of motion, strengthening, and postural correction. Manual therapy included soft tissue techniques and joint mobilization of the cervical spine. Physical modalities were applied to reduce pain and improve function. The intervention was delivered over 5 weeks, with a total of 10 sessions.

Conventional Physiotherapy; Conventional Physiotherapy + Neurodynamic Mobilization

neurodynamic mobilization OTHER

Neurodynamic mobilization consisted of specific neural tissue mobilization techniques targeting the affected cervical nerve roots. The techniques were applied in addition to conventional physiotherapy and aimed to restore normal neural mobility and reduce mechanosensitivity. Treatment was delivered over 5 weeks (10 sessions). Each session included standardized neurodynamic sliding techniques performed within pain-free or low-pain ranges, combined with conventional physiotherapy interventions including therapeutic exercises, manual therapy, and physical modalities. The intervention was individually tailored based on patient symptoms and clinical presentation.

Conventional Physiotherapy + Neurodynamic Mobilization

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 18-65 years.
• Diagnosis of cervical radiculopathy.
• pain radiating to the upper limb.
• Presence of at least one neurological sign, including: Sensory deficit, or Muscle weakness, or Diminished reflexes.

You may not qualify if:

• Previous cervical spine surgery.
• Cervical myelopathy.
• Cervical fractures.
• Tumors affecting the cervical spine.
• Inflammatory disorders.
• Any contraindication to physiotherapy interventions.

Sponsors & Collaborators

• Lebanese German University: lead

Study Sites (1)

Lebanese German University

Jounieh, Beirut, 0000, Lebanon

Location

MeSH Terms

Conditions

Radiculopathy

Condition Hierarchy (Ancestors)

Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases

Study Officials

• Samir Matar, Professor

  Lebanese German University

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Phd Holder, Head of DPT department

Study Record Dates

• First Submitted: May 26, 2026
• First Posted: June 11, 2026
• Study Start: November 1, 2024
• Primary Completion: February 28, 2025
• Study Completion: February 28, 2025
• Last Updated: June 12, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

LE (1)